The Effect of LI4-LI11 Electrical Acupuncture at Unaffected Limb on Cerebral Blood Flow in Ischemic Stroke Patients using SPECT

SPECT를 이용한 뇌경색환자의 건측 합곡-곡지 전침치료가 뇌관류에 미치는 영향

  • Moon, Sang-kwan (Department of Cardiovascular and Neurologic Diseases(Stroke Center), College of Oriental Medicine, Kyung-Hee University) ;
  • Kim, Young-suk (Department of Cardiovascular and Neurologic Diseases(Stroke Center), College of Oriental Medicine, Kyung-Hee University) ;
  • Park, Sung-uk (Department of Cardiovascular and Neurologic Diseases(Stroke Center), College of Oriental Medicine, Kyung-Hee University) ;
  • Jung, Woo-sang (Department of Cardiovascular and Neurologic Diseases(Stroke Center), College of Oriental Medicine, Kyung-Hee University) ;
  • Ko, Chang-nam (Department of Cardiovascular and Neurologic Diseases(Stroke Center), College of Oriental Medicine, Kyung-Hee University) ;
  • Cho, Ki-ho (Department of Cardiovascular and Neurologic Diseases(Stroke Center), College of Oriental Medicine, Kyung-Hee University) ;
  • Bae, Hyung-sup (Department of Cardiovascular and Neurologic Diseases(Stroke Center), College of Oriental Medicine, Kyung-Hee University) ;
  • Lee, Jae-dong (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-Hee University, Institute of Oriental Medicine, Kyung-Hee University) ;
  • Kim, Deok-yoon (Department of Nuclear Medicine, College of Medicine, Kyung-Hee University)
  • 문상관 (경희대학교 한의과대학 제2내과학교실) ;
  • 김영석 (경희대학교 한의과대학 제2내과학교실) ;
  • 박성욱 (경희대학교 한의과대학 제2내과학교실) ;
  • 정우상 (경희대학교 한의과대학 제2내과학교실) ;
  • 고창남 (경희대학교 한의과대학 제2내과학교실) ;
  • 조기호 (경희대학교 한의과대학 제2내과학교실) ;
  • 배형섭 (경희대학교 한의과대학 제2내과학교실) ;
  • 이재동 (경희대학교 한의과대학 침구학교실) ;
  • 김덕윤 (경희대학교 의과대학 핵의학교실)
  • Received : 2003.12.10
  • Accepted : 2004.01.17
  • Published : 2004.02.20

Abstract

Background and purpose: Opposing-needling technique involves selecting acupoints at unaffected limb. The aim of this study was to evaluate the effect of LI4-LI11 electrical acupuncture at unaffected limb on the cerebral blood flow in ischemic stroke patients using SPECT Methods: We selected 9 ischemic stroke patients. Baseline brain SPECT was done with triple head gamma camera(MultiSPECT3, Siemens, USA) after intravenous administration of 925 MBq of Tc-99m ECD). Fifteen-minute electro-acupuncture at Hapgok(LI 4) and Gokji(LI 11) were applied on unaffected upper limb of subjects. The same dose of Tc-99m ECD was injected during the electro-acupuncture, and the second SPECT images were obtained. Using the computer software(ICON 7.1, Siemens, USA), 3 SPECT slices(upper, middle, lower) surrounding the brain lesion were selected and each slice was divided by 10-16 brain regions. Asymmetry indexes were analyzed in each brain region. We regarded$\geq$10% changes of asymmetry index between before and after electro-acupuncture as significance. Results: Seven Patients(77.8%) had significantly increased perfusion and 2(22.2%) didn't show increased perfusion in post-acupuncture scans compared to pre-acupuncture scans(baseline). The regions of CBF improvement were mostly frontal lobes and anterior temporal lobes. Conclusions: This study demonstrated that LI4-LI11 electro-acupuncture at unaffected limb increased regional cerebral blood perfusion to the corresponding brain areas in ischemic stroke patients.

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