Journal of Acupuncture Research
- Volume 21 Issue 3
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- Pages.121-131
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- 2004
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- 2586-288X(pISSN)
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- 2586-2898(eISSN)
The Study of Anti-inflammtory Mechanism with Bee Venom on Human Synoviocytes
인체(人體) 활막세포(滑膜細胞)를 대상으로 한 봉양침액(蜂藥鍼液)의 염증(炎症) 치료(治療) 기전(機轉) 연구(硏究)
- Bae, Chul-woo (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyungwon University) ;
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Song, Ho-sueb
(Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyungwon University)
- Received : 2004.04.19
- Accepted : 2004.05.15
- Published : 2004.06.20
Abstract
Objective : The purpose of this study was investigation how the bee venom(BV) prevents inflammation in human cell. Methods : we induced inflammation on human synoviocyte cell by lipopolysaccharide(LPS) and sodium nitroprusside(SNP), treated the bee venom and melittin on this cell, surveyed the expression of Nisotric oxide(NO), inducible nitric oxide synthase(iNOS), Cyclooxygenease-2(COX-2), cytolic phospholipase