혜화의학회지 (Journal of Haehwa Medicine)
- 제13권2호
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- Pages.97-107
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- 2004
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- 2586-3002(pISSN)
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- 2586-3347(eISSN)
순기활혈탕(順氣活血湯)이 고지혈증(高脂血症)에 미치는 영향(影響)
Study on the Effect of SGHHT on Hyperlipidemia
- Lee, Ki-Seo (Dept. of Pharmacology, Collage of Oriental Medicine, Daejeon Univ.) ;
- Kang, Tak-Lim (Dept. of Pharmacology, Collage of Oriental Medicine, Daejeon Univ.) ;
- Namgung, Uk (Dept. of Neurophysiology, Collage of Oriental Medicine, Daejeon Univ.) ;
- Kim, Dong-Hee (Dept. of Pathology, Collage of Oriental Medicine, Daejeon Univ.)
- 심사 : 2004.10.14
- 발행 : 2004.12.30
초록
As a long-term goal for the development of new prescriptions for hyperlipidemia, SGHHT was examined in the present study using a rat model in which the hyperlipidemia was induced. The major parameters related to lipid metabolism were investigated and the key findings are summarized below. 1. The body weight of hyperlipidemia-induced rats began to show lower body weight beginning one week after SGHHT treatment compared to non-treated control group animals. 2. Cholesterol levels showed a significant decrease beginning three weeks after SGHHT treatment, compared to hyperlipidemia-induced control group. 3. Total cholesterol levels in SGHHT-treated animal group were significantly decreased compared to the hyperlipidemia-induced control group. 4. Glucose levels in SGHHT-treated animal group were significantly decreased compared to the hyperlipidemia-induced control group. 5. Triglyceride levels in SGHHT-treated animal group were significantly decreased compared to the hyperlipidemia-induced control group.6. SGOT levels in SGHHT-treated animal group were significantly decreased compared to the hyperlipidemia-induced control group whereas there was no significant change in SGPT levels. 7. HDL-cholesterol levels were significantly increased in SGHHT- treated animal group compared to the hyperlipidemia-induced control group. 8. LDL-cholesterol levels were significantly decreased in SGHHT-treated animal group compared to the hyperlidemia-induced control group.
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