Journal of Preventive Medicine and Public Health

The Korean Society for Preventive Medicine (대한예방의학회)
권호 표지

Air Pollution Exposure and Health Effects in Fetus

대기오염 노출이 출산시 태아에 미치는 건강영향

  • Lee, Bo-Eun (Medical Research Center, College of Medicine, Inha University) ;
  • Park, Hye-Sook (Department of Preventive Medicine, College of Medicine, Ewha Womans University) ;
  • Kim, Young-Ju (Department of Obstetrics and Gynecology, College of Medicine, Ewha Womans University) ;
  • Park, Eun-Ae (Department of Pediatrics, College of Medicine, Ewha Womans University) ;
  • Hong, Yun-Chul (Department of Preventive Medicine, College of Medicine, Seoul National University) ;
  • Ha, Eun-Hee (Department of Preventive Medicine, College of Medicine, Ewha Womans University)
  • 이보은 (인하대학교 의학연구센타 의과대학) ;
  • 박혜숙 (이화여자대학교 의과대학 예방의학교실) ;
  • 김영주 (이화여자대학교 의과대학 산부인과학교실) ;
  • 박은애 (이화여자대학교 의과대학 소아과학교실) ;
  • 홍윤철 (서울대학교 의과대학 예방의학교실) ;
  • 하은희 (이화여자대학교 의과대학 예방의학교실)
  • Published : 2004.12.01
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Abstract

As there have been growing concerns about the adverse effects of air pollution on birth outcome, studies for this area has been carried out in different populations and sites. We reviewed the epidemiologic studies that evaluated the effects of air pollution on birth outcome such as low birth weight and preterm births. We identified the air pollution exposure during pregnancy was related with low birth weight and preterm birth, although there are differences among studies for the critical period of vulnerability. The biological mechanisms whereby air pollution might influence health of fetus are not clearly established. The exposure to carbon monoxide(CO) during pregnancy could increase fetal carboxyhemoglobin and result in tissue hypoxia. On the other hand, ambient particles less than $10{\mu}m$ in aerodynamic diameter($PM_{10}$) could lead to inflammation and increase blood viscosity. Controlling for potential confounders and valid assessment of exposure are the methodological issues remained in these epidemiologic studies. In the future, more studies are needed to investigate the effect of air pollution on preterm birth or stillbirths, considering the various exposure period and the biological mechanism.

Keywords

References

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