Journal of the Korean Applied Science and Technology (한국응용과학기술학회지)

The Korean Society of Applied Science and Technology (한국응용과학기술학회)
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Preparation of Mesoporous Materials and Thin Films It's Application for DNA Sensor

  • Han, Seung-Jun (Department of Chemical Engineering System, Changwon National University) ;
  • Heo, Soon-Young (Department of Chemical Engineering System, Changwon National University) ;
  • Park, Keun-Ho (Department of Chemical Engineering System, Changwon National University) ;
  • Lee, Soo (Department of Chemical Engineering System, Changwon National University) ;
  • Kim, Byung-Kwan (Department of Chemical Engineering System, Changwon National University) ;
  • Kim, Jin-Heung (Department of Nano Science, Ewha Womans University)
  • Published : 2004.12.31
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Abstract

Highly ordered pure-silica MCM-41 materials possessing well-defined morphology have been successfully prepared with surfactant used as a template. The fabrication of mesoporous silica has received considerable attention due to the need to develop more efficient materials' for catalysis, separations, and chemical sensing. The surface modified MCM-41 was used as anadsorbent for biomolecules. Silica-supported organic groups and DNA adsorption on surface modified MCM-41 were investigated by FT-IR and UV-Vis spectrometer, respectively. The use of MCM-41 as the modification of electrode surfaces were investigated electrochemical properties of metal mediators with biomolecules. The modified ITO electrodes increased peak currents for a redox process of $[Ru(bpy)_3]^{2+}$ relative to the bare electrode. The electrochemical detection of DNA by cyclic voltammetry when the current is saturated in the presence of the mediator appeared more sensitive due to a higher catalytic current on the MCM-41 supported electrodes modified by carboxylic acid functional groups. The carboxyl or amine groups on the surface of MCM-41 interact and react with the $-NH_2$ groups of guanine and backbone, respectively. Highly ordered mesoporous materials with organic groups could find applications as DNA sensors.

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References

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