Journal of Periodontal and Implant Science

Korean Academy of Periodontology (대한치주과학회)
권호 표지

The effect of new bone formation of titanium mesh and demineralized freeze-dried bone

천공형 티타늄막과 탈회동결건조골의 신생골 형성에 대한 영향

  • Lee, Yun-Ho (Department of Periodontology, Kyung Hee University) ;
  • Park, Joon-Bong (Department of Periodontology, Kyung Hee University) ;
  • Kwon, Young-Hyuk (Department of Periodontology, Kyung Hee University) ;
  • Herr, Yeek (Department of Periodontology, Kyung Hee University) ;
  • Kim, Chong-Kwan (Dept of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry and Brain Korea 21 Project of Medical Sciences, Younsei University)
  • 이윤호 (경희대학교 치과대학 치주과학교실) ;
  • 박준봉 (경희대학교 치과대학 치주과학교실) ;
  • 권영혁 (경희대학교 치과대학 치주과학교실) ;
  • 허익 (경희대학교 치과대학 치주과학교실) ;
  • 김종관 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소, BK21 의과학 사업단)
  • Published : 2004.03.30
Download PDF
⟨ Previous Next ⟩

Abstract

This study was performed to evaluate bone formation in the calvaria of rabbit by the concept of guided bone regeneration with titanium mesh membrane and demineralized freeze-dried bone. The animal was sacrificed at 2 weeks, 4 weeks, 8 weeks, and 12 weeks after the surgery. Non-decalcified specimens were processed for histologic analysis. 1. The titanium mesh but the biocompatibility was excellent the cell-occlusiveness was feeble. 2. The cell-occlusiveness was feeble and also the soft tissue growth of the upper part of the newly-formed bone after operating was excellent in early stage. 3. The maintenance ability of the space for the GBR very was excellent. 4. The titanium mesh the tissue-integration was superior the wound fixation ability excellent. 5. The demineralized freeze-dried bone did not promote the bone regeneration. 6. With the lapse of time, formation quantity of the bone some it increased, it increased quantity very it was feeble. Within the above results, the titanium mesh for the guided bone regeneration was excellent, the dεmineralized freeze-dried bone confirmed does not promote bone regeneration.

Keywords

References

  1. Melcher AH. On the repair potential of periodontal tissues. J Periodontol. 1976. 47 : 256-260
  2. Gould TR, Melcher AH, Brunette DM. Migration and division of progenitor cell populations in periodontal ligament after wounding. J Periodontal Res. 1980. 15 : 20-42
  3. Roberts WE, Mozsary PG, Klingler E. Nuclear size as a cell-kinetic marker for osteoblast differentiation. Am J Anat. 1982. 165 : 373-384
  4. McCulloch CA, Melcher AH. Cell density and cell generation in the per- iodontal ligament of mice. Am J Anat. 1983. 167: 43-58
  5. Nyman S, Lindhe J, Karring T. New attachment following surgical treatment of human peridontal disease. J Clin Periodontol. 1982. 9 : 290-296
  6. Gottlow J, Nyman S, Lindhe J, Karring T, Wennstrom J. New attachment for- mation in the human periodontium by guided tissue regeneration. Case reports. J Clin Periodontol. 1986. 13 : 604-616
  7. Dahlin C, Lindhe A, Gottlow J. Healing of bone defects by guided tissue regeneration. Plast Reconstr Surg. 1988. 81 : 672
  8. Linde A, Thoren C, Dahlin C, Sanberg E. Creation of new bone by an osteopromotive membrane technique. An experimental study in monkeys. Scand. J Plast Reconstr Surg. 1990. 24 : 13
  9. Hammerle CHF, Schmid J, Olah AJ, Lang NP. Osseous healing of experi- mentally created defects in the calvaria of rabbits using guided bone regenera- tion. A pilot study. Clin Oral Impl Res. 1992. 3 : 144
  10. Linde A, Thoren C, Dahlin C, Sandberg E. Creation of new bone by an osteo- promotive membrane technique. J Oral Maxillofac Surg. 1993. 51:892-897
  11. Tinti C, Vincenzi G, Cochetto R. Guided tissue regeneration in mucogingival surgery. J Periodontol. 1993. 64 : 1184-1191
  12. Jovanovic SA, Schenk RK. Supracrestal bone formation around dental implants. An experimental dog study. Int J Oral Maxillofac Implants. 1995. 10 : 23
  13. Simion M, Trisi P, Piattelli A. Vertical ridge augmentation using a membrane technique associated with osseointegrated implants. Int J Periodont Rest Dent. 1994. 14 : 497
  14. Tinti C, Benfenati SP, Polizzi G. Vertical ridge augmentation : what is the limit? Int J Periodont Rest Dent. 1996. 16 : 221
  15. Schmid J, Hammerle CH, Olah AJ, Lang NP. Membrane permeability is unnecessary for guided generation of new bone. An experimental study in the rabbit. Clin Oral Implants Res. 1994. 5 :125-130
  16. von Arx T, Hardt N, Wallkamm B. The TIME technique: a new method for localized alveolar ridge augmentation prior to placement of dental implants. Int J Oral Maxillofac Implants. 1996. 11 : 387-394
  17. Malchiodi L, Scarano A, Quaranta M, Piattelli A. Rigid fixation by means of titanium mesh in edentulous ridge expansion for horizontal ridge aug- mentation in the maxilla. Int J Oral Maxillofac Implants. 1998. 13 : 701-705
  18. Van Steenberghe D, Johansson C, Quirynen M, Molly L, Albrektsson T, Naert I. Bone augmentation by means of a stiff occlusive titanium barrier. Clin Oral Implants Res. 2003. 14 : 63-71
  19. Lozada J, Proussaefs P. Clinical radiographic and histologic evaluation of maxillary bone reconstruction by using a titanium mesh and autogenous iliac graft: a case report. J Oral Implantol. 2002. 28 : 9-14
  20. Proussaefs P, Lozada J, Kleinman A, Rohrer MD, McMillan PJ. The use of titanium mesh in conjunction with autogenous bone graft and inorganic bovine bone mineral (bio-oss) for localized alveolar ridge augmentation: a human study. Int J Periodontics Restorative Dent. 2003. 23 : 185-195
  21. Assenza B, Piattelli M, Scarano A, Lezzi G, Petrone G, Piattelli A. Localized ridge augmentation using titanium micromesh. J Oral Implantol. 2001. 27 : 287-292
  22. Artzi Z, Dayan D, Alpern Y, Nem- covsky CE. Vertical ridge augmentation using xenogenic material supported by a configured titanium mesh: clinicohis-topathologic and histochemical study. Int J Oral Maxillofac Implants. 2003. 18 : 440-446
  23. Buser D, Dahlin C, Schenk RK. Guided bone regeneration in implant dentistry. Quintessence, 1996
  24. Becker W, Lynch SE, Lekholm U, Becker BE, Caffesse R, Donath K, Sanchez R. A comparison of ePTFE membranes alone or in combination with platelet- derived growth factors and insulin-like growth factor-I or demineralized freeze-dried bone in pro- moting bone formation around imme- diate extraction socket implants. J Periodontol. 1992. 63 : 929-940
  25. Becker W, Becker BE, Caffesse R. A comparison of demineralized freeze- dried bone and autologous bone to induce bone formation in human extrac- tion sockets. J Periodontol. 1994. 65 : 1128-1133
  26. Becker W, Urist MR, Tucker LM, Becker BE, Ochsenbein C. Human demineralized freeze-dried bone: Inadequate induced bone formation in athymic mice. A preliminary report. J Periodontol. 1995. 66 : 822-828
  27. Becker W, Schenk R, Higuchi K, Lekholm U, Becker BE. Variations in bone regeneration adjacent to implants augmented with barrier membranes alone or with demineralized freeze-dried bone or autologous grafts : A study in dogs. Int J Oral Maxillofac implants. 1995. 10 : 143-154
  28. Becker W, Urist M, Becker BE, Jackson W, Parry DA, Bartold M, Vincenzzi G, De Georges D, Niederwanger M. Clinical and histologic observations of sites implanted with intraoral autologous bone grafts or allografts. 15 human case reports. J Periodontol. 1996. 67 : 1025-1033
  29. Nevins M, Mellonig JT. Enhancement of the damaged edentulous ridge to receive dental implants. A combination of allograft and the Gore-Tex membrane. Int J Periodont Rest Dent. 1992. 12 : 97
  30. Simion M, Dahlin C, Trisi P, Piattelli A. Qualitative and quantitative com- parative study on different filling mat- erials used in bone tissue regeneration : A controlled clinical study. Int J Periodontics Restorative Dent. 1994. 14 : 198-215
  31. Simion M, Trisi P, Piattelli A. GBR with an ePTFE membrane associated with DFDBA : Histologic and histoch- emical analysis in a human implant retrieved after 4 years of loading. Int J Periodontics Restorative Dent. 1996. 16 : 338-347
  32. Wlodarski KH, Brodzikowska A. Ability of commercial demineralized freeze- dried bone allograft to induce new bone formation. J Periodontol. 1996. 67 : 918-926
  33. Majzoub Z, Berengo M, Giardino R, Cordioli G. Role of intramarrow penetration in osseous repair : A pilot study in the rabbit calvaria. J Periodontol. 1999. 70 : 1501-1510
  34. Schenk RK, Hardwick WR, Dahlin C. Healing pattern of bone regeneration in membrane-protected defects. A histologic study in the canine mandible. Int J Oral Maxillofac Implants. 1994. 9 : 13-29
  35. Schimid J, Wallkamm B, Hammerle CHF, Gogolewski S, Lang NP. The significance of angiogenesis in guided bone regeneration. A case report of a rabbit experiment. Clin Oral Impants Res. 1997. 8 : 244-248
  36. Leghissa GC, Zaffe D, Assenza B, Botticelli AR. Guided bone regeneration using titanium grids: report of 10 cases. Clin Oral Implants Res. 1999. 10 : 62-8
  37. Assenza B, Piattelli M, Scarano A, Lezzi G, Petrone G, Piattelli A. Localized ridge augmentation using titanium micromesh.J Oral Implantol. 2001. 27 : 287-92
  38. Degidi M, Scarano A, Piattelli A. Regeneration of the alveolar crest using titanium micromesh with autologous bone and a resorbable membrane. J Oral Implantol. 2003. 29 : 86-90