대한의생명과학회지 (Biomedical Science Letters)
- 제10권3호
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- Pages.259-262
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- 2004
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- 1738-3226(pISSN)
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- 2288-7415(eISSN)
Effect of Carrageenan on the Tendon of Skeletal Muscle of the Rat
- Hong Gi-Youn (Department of Obstetrics and Gynecology, School of Medicine, Wonkwang University) ;
-
Park Seung-Taeck
(Department of Obstetrics and Gynecology, School of Medicine, Wonkwang University)
;
- Jekal Seung-Joo (Department of Clinical Pathology, Wonkwang Health Science College) ;
- Lee Kang-Chang (Department of Obstetrics and Gynecology, School of Medicine, Wonkwang University)
- 발행 : 2004.09.01
초록
The aim of present study was to examine the effect of carrageenan on the tendon of skeletal muscle of rat. The tendon damage was induced by injection of carrageenan into skeletal hind muscle of rats. Rats were killed on 48 hours after carrageenan injection. The resulting tendons were fixed with 10％ neutral buffered formalin (NBF), dehydrated, embedded, sectioned by 4 μm, and stained by phosphotungstic acid hematoxylin (PTAH) or hematoxylin-eosin (H-E). Carrageenan induced the segregation of tendon fibers, intratendinous cleft, segregation of muscle cell group, wave arrangement of tendon fiber. The results suggest that carrageenan induced tendon damage of rat's skeletal muscle by morphological changes.