Imaging Science in Dentistry
- 제34권2호
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- Pages.75-79
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- 2004
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- 2233-7822(pISSN)
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- 2233-7830(eISSN)
낭성법랑모세포종, 함치성낭, 치성각화낭의 방사선소견과 Ki-67, PCNA, Cytokeratin 발현과의 연관성에 관한 연구
Relation of the radiologic findings and labeling index of Ki-67, PCNA and cytokeratin in unicystic ameloblastoma, dentigerous cyst and odontogenic keratocyst
- 송만용 (서울대학교 치과대학 구강악안면방사선학교실) ;
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이삼선
(서울대학교 치과대학 구강악안면방사선학교실, 치학연구소 및 BK21) ;
- 이진구 (서울대학교 치과대학 구강악안면방사선학교실) ;
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이원진
(서울대학교 치과대학 구강악안면방사선학교실, 치학연구소 및 BK21) ;
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허민석
(서울대학교 치과대학 구강악안면방사선학교실, 치학연구소 및 BK21) ;
- 이재일 (서울대학교 치과대학 구강병리학교실) ;
- 민병무 (서울대학교 치과대학 구강생화학교실) ;
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최순철
(서울대학교 치과대학 구강악안면방사선학교실, 치학연구소 및 BK21)
- Song Man-Yong (Dept. of Oral and Maxillofacial Radiology, College of Dentistry, Seoul National University) ;
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Lee Sam-Sun
(Dept. of Oral and Maxillofacial Radiology, Dental Research Institute, and BK21, College of Dentistry, Seoul National University) ;
- Lee Jin-Koo (Dept. of Oral and Maxillofacial Radiology, College of Dentistry, Seoul National University) ;
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Lee Won-Jin
(Dept. of Oral and Maxillofacial Radiology, Dental Research Institute, and BK21, College of Dentistry, Seoul National University) ;
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Heo Min-Suk
(Dept. of Oral and Maxillofacial Radiology, Dental Research Institute, and BK21, College of Dentistry, Seoul National University) ;
- Lee Jae-Il (Dept. of Oral Pathology, College of Dentistry, Seoul National University) ;
- Min Byung-Moo (Dept. of Oral Biochemistry, College of Dentistry, Seoul National University) ;
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Choi Soon-Chul
(Dept. of Oral and Maxillofacial Radiology, Dental Research Institute, and BK21, College of Dentistry, Seoul National University)
- 발행 : 2004.06.01
초록
Purpose: To compare the proliferation potential of the epithelial cells between unicystic ameloblastoma (UA), dentigerous cyst (DC), and odontogenic keratocyst (OKC) and to correlate this proliferation potential with the radiographic features of these three pathoses. Materials and Methods: Immunohistochemical expression of PCNA, Ki-67, and cytokeratin as a proliferation marker were assessed for 15 cases of UA, 15 cases of DC, and 15 cases of OKC. The degree of immunochemical expression of three proliferation markers were correlated with the radiographic features, especially cortical expansion (negative and positive) and shape of border (scalloped and round). Results: Using PCNA and Ki-67, OKC showed the highest proliferation potential and UA the lowest. Statistically significant differences were found between the OKC and the UA (p < 0.05). However, no statistically significant difference was present according to the radiographic features in all pathoses. Using cytokeratin, there was no significant differences of proliferation potential among three pathoses. Conclusions : OKC epithelium has the most intense proliferation potential, followed by the dentigeous cyst and then unicystic ameloblastoma. There is no significant relation between the radiographic features and the proliferation potential of epithelium of these three pathoses.