References
- Appella E and Anderson CW (2000) Signaling to p53: breaking the posttranslational modification code. Pathol Biol 48: 227-245
- Baek KH, Kim MS, Kim YS, Shin JM, and Choi HK (2004) DUB1A, a novel deubiquitinating enzyme subfamily member, is polyubiquitinated and cytokine-inducible in B-lymphocytes. J Biol Chem 279: 2368-2376 https://doi.org/10.1074/jbc.M304774200
- Chau V, Tobias JW, Bachmair A, Marriott D, Ecker DJ, Gonda DK, and Varshavsky A (1989) A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein. Science 243: 1576-1583 https://doi.org/10.1126/science.2538923
- Ciechanover A (1998) The ubiquitin-proteasome pathway: on protein death and cell life. EMBO J 17: 7151-7160 https://doi.org/10.1093/emboj/17.24.7151
- Cummins JM and Vogelstein B (2004) HAUSP is required for p53 destabilization. Cell Cycle 3: 689-692
- Everett RD, Meredith M, Orr A, Cross A, Kathoria M, and Parkinson J (1997) A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein. EMBO J 16: 1519-1530 https://doi.org/10.1093/emboj/16.7.1519
- Freiman RN and Tjian R (2003) Regulating the regulators: lysine modifications make their mark. Cell 112: 11-17 https://doi.org/10.1016/S0092-8674(02)01278-3
- Glickman MH and Ciechanover A (2002) The ubiquitinproteasome proteolytic pathway: destruction for the sake of construction. Physiol Rev 82: 373-428
- Haupt Y, Maya R, Kazaz A, and Oren M (1997) Mdm2 promotes the rapid degradation of p53. Nature 387: 296-299 https://doi.org/10.1038/387296a0
- Hershko A and Ciechanover A (1998) The ubiquitin system. Annu Rev Biochem 67: 425-479 https://doi.org/10.1146/annurev.biochem.67.1.425
- Honda R, Tanaka H, and Yasuda H (1997) Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett 420: 25-27 https://doi.org/10.1016/S0014-5793(97)01480-4
- Hu M, Li P, Li M, Li W, Yao T, Wu JW, Gu W, Cohen RE, and Shi Y (2002) Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde. Cell 111: 1041-1054 https://doi.org/10.1016/S0092-8674(02)01199-6
- Kim JH, Park KC, Chung SS, Bang O, and Chung CH (2003) Deubiquitinating enzymes as cellular regulators. J Biochem 134: 9-18 https://doi.org/10.1093/jb/mvg107
- Kubbutat MH, Jones SN, and Vousden KH (1997) Regulation of p53 stability by Mdm2. Nature 387: 299-303 https://doi.org/10.1038/387299a0
- Layfield R, Alban A, Mayer RJ, and Lowe J (2001) The ubiquitin protein catabolic disorders. Neuropathol Appl Neurobiol 27: 171-179 https://doi.org/10.1046/j.1365-2990.2001.00335.x
- Li M, Brooks CL, Kon N, and Gu W (2004) A dynamic role of HAUSP in the p53-Mdm2 pathway. Mol Cell 13: 879-886 https://doi.org/10.1016/S1097-2765(04)00157-1
- Li M, Chen D, Shiloh A, Luo J, Nikolaev AY, Qin J, and Gu W (2002) Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization. Nature 416: 648-653 https://doi.org/10.1038/nature737
- Lim SK, Shin JM, Kim YS, and Baek KH (2004) Identification and characterization of murine mHAUSP encoding a deubiquitinating enzyme that regulates the status of p53 ubiquitination. Int J Oncol 24: 357-364
- Menard R, Carriere J, Laflamme P, Plouffe C, Khouri HE, Vernet T, Tessier DC, Thomas DY, and Storer AC (1991) Contribution of the glutamine 19 side chain to transition-state stabilization in the oxyanion hole of papain. Biochemistry 30: 8924-8928 https://doi.org/10.1021/bi00101a002
- Pickart CM (2001) Mechanisms underlying ubiquitination. Annu Rev Biochem 70: 503-533 https://doi.org/10.1146/annurev.biochem.70.1.503
- Quesada V, Diaz-Perales A, Gutierrez-Fernandez A, Garabaya C, Cal S, and Lopez-Otin C (2004) Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases. Biochem Biophys Res Commun 314: 54-62 https://doi.org/10.1016/j.bbrc.2003.12.050
- Salomoni P and Pandolfi PP (2002) p53 De-ubiquitination: at the edge between life and death. Nat Cell Biol 4: E152-153 https://doi.org/10.1038/ncb0602-e152
- Sui G, Affar el B, Shi Y, Brignone C, Wall NR, Yin P, Donohoe M, Luke MP, Calvo D, Grossman SR, and Shi Y (2004) Yin Yang 1 is a negative regulator of p53. Cell 117: 859-872 https://doi.org/10.1016/j.cell.2004.06.004
- Vugmeyster Y, Borodovsky A, Maurice MM, Maehr R, Furman MH, and Ploegh HL (2002) The ubiquitin-proteasome pathway in thymocyte apoptosis: caspase-dependent processing of the deubiquitinating enzyme USP7 (HAUSP). Mol Immunol 39: 431-441 https://doi.org/10.1016/S0161-5890(02)00123-2
- Wilkinson KD (2000) Ubiquitination and deubiquitination: targeting of proteins for degradation by the proteasome. Semin Cell Dev Biol 11: 141-148 https://doi.org/10.1006/scdb.2000.0164