골수 이식을 받은 만성 골수성 백혈병 환자의 Tc-99m MDP 골스캔에서 우연히 발견된 비장 Hemochromatosis

Splenic Hemochromatosis Incidentally Found on Tc-99m MDP Bone Scan in a Chronic Myelogenous Leukemia Patient who Received Bone Marrow Transplantation

  • 서지형 (경북대학교 의과대학 핵의학교실) ;
  • 배진호 (경북대학교 의과대학 핵의학교실) ;
  • 정신영 (경북대학교 의과대학 핵의학교실) ;
  • 이재태 (경북대학교 의과대학 핵의학교실) ;
  • 이규보 (경북대학교 의과대학 핵의학교실) ;
  • 안병철 (경북대학교 의과대학 핵의학교실)
  • Seo, Ji-Hyoung (Department of Nuclear Medicine, Kyungpook National University Hospital, Kyungpook National University Medical School) ;
  • Bae, Jin-Ho (Department of Nuclear Medicine, Kyungpook National University Hospital, Kyungpook National University Medical School) ;
  • Jeong, Sin-Young (Department of Nuclear Medicine, Kyungpook National University Hospital, Kyungpook National University Medical School) ;
  • Lee, Jae-Tae (Department of Nuclear Medicine, Kyungpook National University Hospital, Kyungpook National University Medical School) ;
  • Lee, Kyu-Bo (Department of Nuclear Medicine, Kyungpook National University Hospital, Kyungpook National University Medical School) ;
  • Ahn, Byeong-Cheol (Department of Nuclear Medicine, Kyungpook National University Hospital, Kyungpook National University Medical School)
  • 발행 : 2004.02.28

초록

Purpose: Tc-99m MDP bone scan was performed to evaluate a generalized bone pain in a 24-year-old male chronic myelogenous leukemia patient who received bone marrow transplantation at 7 months ago. The patient had received large amounts of blood transfusion for managing symptoms related to anemia. Bone scan revealed substantial splenic tracer uptake. Magnetic resonance image and laboratory evidence of hemochromatosis suggests that the presence of large quantities of iron in the spleen of this patient may have been responsible for the splenic uptake of the bone scanning agent. The authors report a case of splenic hemochromatosis incidentally found on Tc-99m MDP bone scan.

키워드

참고문헌

  1. Sabnis SS, Blend MJ. Splenic uptake of Tc-99m MDP in a patient with hemochromatosis. Clin Nucl Med 1999;24:622-3 https://doi.org/10.1097/00003072-199908000-00024
  2. Kornreich L, Horev G, Yaniv I, Stein J, Grunebaum M, Zaizov R. Iron overload following bone marrow transplantation in children: MR findings. Pediatr Radiol 1997;27:869-72 https://doi.org/10.1007/s002470050259
  3. Valdez VA, Jacobstein JG. Visualization of the liver with 99mTc-EHDP in thalassemia major. Gastrointest Radiol 1981;6:175-6 https://doi.org/10.1007/BF01890245
  4. Salo S, Alanen A, Leino R, Bondestam S, Komu M. The effect of haemosiderosis and blood transfusions on the T2 relaxation time and 1/T2 relaxation rate of liver tissue. Br J Radiol 2002;75:24-7 https://doi.org/10.1259/bjr.75.889.750024