Hepatotoxicity Assessment of Derived Product from Pyrolysis System for Waste Plastic Recycling

폐플라스틱 재활용을 위한 열분해공정 파생물질의 간독성 평가

  • 신혜순 (덕성여자대학교 약학대학)
  • Published : 2004.06.01

Abstract

Recently, waste plastic recycling technology is transforming from Incineration system to pyrolysis gasification system which can derive the resources from environmental waste and charge no more environmental burden to nature. The present study was carried out to investigate the potential acute toxicity of derived product of pyrolysis gasifications system for recycling of waste plastic by a single oral dose in Sprague-Dawley Rats. In order to evaluate the hepatotoxic effects of derived product of pyrolysis gasification system, activities of serum transaminase were measured in rats. No related changes in survivals, clinical signs and the ratio of the liver to body weights of rats were monitored. The results showed that the single oral administration of material of pyrolysis system for recycling of waste plastic did not induce any toxic effect at orally single dose level of 0 and 100, 200, 400, 800mg/kg body weight in rats. We could not find out any significant tocxicity induced by single oral administrate of material of pyrolysis system for recycling of waste plastic.

Keywords

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