Isolation and Cultural Characteristics of Styrene Dimer [Endocrine Disrupter] Biodegrading Microorganism

Styrene dimer [환경호르몬 물질] 분해균주의 분리 및 배양특성

  • 오경택 (전남대학교 환경공학과) ;
  • 류인재 (전남대학교 환경공학과) ;
  • 강창민 (초당대학교 환경공학과) ;
  • ;
  • 정선용 (전남대학교 환경공학과)
  • Published : 2004.08.01

Abstract

We examined the culture conditions and degrading characteristics of styrene dimer (endocrine disrupter) using microorganism. The isolated microbe were consisted of 3 kinds of strain. The strains were identified to Pseudomonas sp. and Klebsiella pneumoniae by API 20E kit, but one was not identified. Single strain was not grown on the C-medium containing styrene dimer. However the complex strain YH3 could grow and we confirmed it by the broth color and O.D$_{660nm}$ (optical density 660 nm). The optimal culture conditions of complex strain YH3 were 35$^{\circ}C$, 1,000 ppm (v/v) of styrene dimer and pH 7.0, respectively. In tolerance test against the organic solvents, the complex strain YH3 could grow above log P=3.1, and could degrade ethyl benzene and 2,4-D, one kind of herbicide. As a result of TLC (Thin Layer Chromatography) analysis, we confirmed that the metabolite of styrene dimer was created by YH3 after 5th day, but not at control samples.

본 연구에서는 환경호르몬 물질의 하나인 스티렌 다이머를 분해하는 미생물을 자연계로부터 분리하고자 하였다. 분리결과 스티렌 다이머 분해 능력이 있는 strain YH3를 분리하였다. Strain YH3은 단일균주가 아닌 3종류의 서로 다른 미생물상을 이루고 있었다. 동정을 한 결과 strain YH32는 Pseudomonas sp.로, strain YH33은 Klebsiella pneumoniae로 동정되었으나, strain YH31은 동정이 되지 않았다. 이들 세균주는 단일균 혹은 두 종류씩 짝을 지어 배양 하여도 스티렌 다이머를 분해하지 못하였으나 세 균주가 혼합되었을 때는 O. $D_{660nm}$ 값과 색도의 변화를 통해 생장을 확인 할 수 있었다. 세 균이 혼합된 복합균주 YH3을 대상으로 균주의 최적 생장 조건을 검토한 결과, 35$^{\circ}C$, pH 7.0, 기질 농도 1,000ppm (v/v)으로 각각 조사되었다. 또한, 유기용매에 대한 내성은 복합균주 YH3는 logP 값이 3.1 이상에서 생장하였고, 방향족화합물인 ethyl benzene과 제초제의 일종인 2,4-D를 분해하였다. 그러나 benzene, toluene, xylene 및 styrene trimer는 분해가 어려운 것으로 확인되었다. 그리고 TLC 분석 결과, 배양 5일째부터 스티렌 다이머의 중간대사산물이 관찰되었다.

Keywords

References

  1. J. Korea Society of Waste Management v.20 Recent Research and Development of Waste Plastics Degradation by Catalytic Pyrolysis Park, Y. K.;J. S. Kim;J. H. Choi;J. K. Jeon;S. D. Kim;S. S. Kim;J. M. Kim;K. S. Yoo
  2. J. of Korea Inst. of Resources Recycling v.8 Current Status and Future Prospects for Foam-Styrene Recycling in Korea Choi, J. S.
  3. Appl. Environ. Microbiol. v.38 Biodegradation of Polystyrene, Poly(methyl methacrylate), and Phenol Formaldehyde David, L. K.;R. Hartenstein;J. Shutter
  4. Appl. Environ. Microbiol. v.58 Biodegradation of Bisphenol A and Other Bisphenols by a Gram-Negatine Aerobic Bacterium Robos, J. H.;T. K. Leib;T. M. Su
  5. Appl. Environ. Microbiol. v.59 Microbial Degradation of Dibenzofuran, Flourene, and Dibenzo-p-dioxin by Staphylococcus auriculans DBF63 Monna, L.;T. Omori;T. Kotama
  6. Appl. Environ. Microbiol. v.61 Multiple genes encoding 2,3-dihydrobiphenyl dioxygenase-1,2-dioxygenase in the Gram-positive polychlorinated biphenyl degrading bacterium Rhodococcus erythropolis TA421 isolated from a termite ecosystem Maeda, M.;S. Y. Chung;E. Song;T. Kudo
  7. 환경부 홈페이지
  8. Kor. J. Biotechnol. Bioeng. v.18 The optimum culture condition for the increasement of biosurfactant produced by Pseudomonas aeruginosa F722 Oh, K. T.;C. M. Kang;S. Y. Chung
  9. Ph. D. Dissertation, Department of Environmental Engineering, Graduate School Chonnam National University Degrading characteristics of hydrocarbon and enhancement of biosurfactant production by crude oil-degrading microorganisms Oh, K. T.
  10. M. S. Thesis, Dept. of Environmental Engineering, Graduate School Chonnam National University Characterization of PCBs-Degrading Bacteria and Related Genes Na, K. S.
  11. Bergey's Manual of Systematic Bacteriology Krieg, N. R.
  12. Biosci. Biotech. Biochem. v.56 Isolation of novel toluene-tolerant strain of Pseudomonas aeruginosa Aono, R.;M. Ito;A. Inoue;K. Horikoshi https://doi.org/10.1271/bbb.56.145
  13. Plant Drug Analysis Wagner, H.;S. Bladt;E. M. Igainski
  14. Kor. J. Appl. Micorbiol. Biotechnol. v.27 Surface-activity and Environmental Characteristics of Biosurfactant Produced by Pseudomonas aeruginosa JRT-4 Hwang, K. A.;J. R. Lee;S. J. Kim;Y. S. Kim;H. J. Ahn
  15. Annual Review of Microbiol. v.3 The growth of bacterial cultures Monod, J. https://doi.org/10.1146/annurev.mi.03.100149.002103
  16. Appl. Environ. Microbiol. v.62 Toluene and ethylbenzene oxidation by purified naphthalene dioxygenase from Pseudomonas sp. strain NCIB 9816-4 Lee, K.;D. T. Gibson
  17. CJ주식회사 식품안전연구센터 홈페이지