Extraction of Acanthoside-D from Acanthopanax Cortex using Supercritical Carbon Dioxide

초임계 이산화탄소를 이용한 가시오갈피로부터 Acanthoside-D의 추출

  • Published : 2004.08.01

Abstract

The purpose of this study was to find an optimum extraction condition of acanthoside-D from acanthopanax cortex with supercritical carbon dioxide as a solvent. In this effort, effects of the extraction conditions including pressure, temperature and presence or absence of a cosolvent on the extraction efficiency were investigated. The ethanol, water or 50% methanol was used as a cosolvent whilst the operating pressure ranged from 200 bar to 300 bar. The acanthoside-D concentrations were determined by means of HPLC equipped with a UV detector. From the results, it was observed that increase of higher pressure led to the higher extraction efficiency. Further, water was found to be the best cosolvent among the entrainers tested.

초임계 이산화탄소를 이용하여 가시오갈피로부터 유용성분인 acanthoside-D를 추출하여 다음과 같은 결론을 유추하였다. 에탄올과 물, 그리고 50% 메탄올을 공용매로 사용하여 일정압력과 온도에서 추출한 결과물에서의 수율이 가장 높게 측정되었으며, 압력의 변화에 따른 acanthoside-D의 추출효율을 비교한 결과 300 bar에서 가장 높은 추출효율을 나타내었다. 또한 50% 메탄올을 공용매로 하여 유량을 변화시킨 결과, 높은 유량에서 높은 수율을 나타내었으나 1.5ml/g 이상의 유량에서는 수율의 변화가 없었다.

Keywords

References

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