Archives of Pharmacal Research

  • 제27권11호
  • /
  • Pages.1106-1108
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  • 2004
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  • 0253-6269(pISSN)
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  • 1976-3786(eISSN)
대한약학회 (The Pharmaceutical Society of Korea)
권호 표지

Gymnastone, A New Benzofuran Derivative from Gymnaster koraiensis

  • Dat, Nguyen-Tien (College of Pharmacy, Chungnam National University) ;
  • Kiem, Phan-Van (Institute of Natural Products Chemistry, Academy of Sciences and Technology, Hanoi, Vietnam) ;
  • Cai, Xing-Fu (College of Pharmacy, Chungnam National University) ;
  • Shen, Quanghai (College of Pharmacy, Chungnam National University) ;
  • Bae, Ki-Hwan (College of Pharmacy, Chungnam National University) ;
  • Kim, Young-Ho (College of Pharmacy, Chungnam National University)
  • 발행 : 2004.11.01
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초록

A new benzofuran derivative, named gymnastone [5-hydroxy-6-acetyl-2-(2-propane-1,2,3-triol)-benzofuran (1)], was isolated from the aerial part of Gymnaster koraiensis, together with viscidone (2) by repeated column chromatography. The structures of both compounds were identified by physico-chemical and spectral analysis including COSY, HMQC, and HMBC experiments.

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참고문헌

  1. Bohlmann, F., Kramp, W., Grenz, M., Robinson, H., and King, R. M., Diterpenes from Baccharis species. Phytochemistry, 20, 1907-1913 (1981) https://doi.org/10.1016/0031-9422(81)84033-2
  2. Breuer, M., Budzikiewicz, H., Siebertz, R., and Proksch, P., Benzofuran derivatives from Ageratum houstonianum. Phytochemistry, 26, 3055-3057 (1987) https://doi.org/10.1016/S0031-9422(00)84592-6
  3. Jung, H. J., Min, B. S., Park, J. Y., Kim, Y. H., Lee, H. K., and Bae, K. H., Gymnasterkoreaynes A-F, cytotoxic polyacetylenes from Gymnaster koraiensis. J. Nat. Prod., 65, 897-901 (2002) https://doi.org/10.1021/np0104018
  4. Ngo, L. V. and Pham, T. V. C., An unusual m-hydroxyaceto-phenone and three new chromanone derivatives from Chrysothamnus viscidiflorus. Phytochemistry, 20, 485-487 (1981) https://doi.org/10.1016/S0031-9422(00)84171-0
  5. Park, J. Y., Min, B. S., Jung, H. J., Kim, Y. H., Lee, H. K., and Bae K. H., Polyacetylene glycosides from Gymnaster koraiensis. Chem. Pharm. Bull., 50, 685-687 (2002) https://doi.org/10.1248/cpb.50.685