쇼크로 이행한 체외순환 후의 전신성 염증반응 증후군 치험 -1예 보고-

Treatment of Systemic Inflammatory Response Syndrome (SIRS) Following Open Heart Surgery Developed into Shock - A case report-

  • 이동석 (한림대학교 의과대학 흉부외과학교실) ;
  • 신윤철 (한림대학교 의과대학 흉부외과학교실) ;
  • 김응중 (한림대학교 의과대학 흉부외과학교실) ;
  • 지현근 (한림대학교 의과대학 흉부외과학교실)
  • 발행 : 2004.11.01

초록

호흡곤란을 주소로 55세 남자 환자가 입원하였다. 환자는 급성 심근 경색에 의한 심부전으로 진단 받은 후 체외순환 하에서 관상 동맥 우회술을 시행하였다. 수술 후 1일째 발열, 백혈구 증가증, 빈맥, 빈호흡 등의 증상을 보이기 시작하면서 전신혈관저항이 감소하고 전신성 염증반응 증후군이 발생하면서 쇽으로 이행하였다. 환자는 고용량(36$\mu$g/min)의 norepinephrine으로 치료하였으며 회복되어 퇴원하였다.

A 55 year old male was admitted for dyspnea. The patient was diagnosed as acute myocardiac infarction, and coronary artery bypass grafting was performed with cardiopulmonary bypass. At postoperative day #1, Systemic Inflammatory Response Syndrome was developed with fever, leukocytosis, tachycardia, tachypnea and low systemic vascular resistance. The patient was recovered after being treated with high dose of (36 $\mug/min)$ norepinephrine, and was discharged.

키워드

참고문헌

  1. Members of the American College of Chest Physicians/ Society of Critical Care Medicine Consensus Conference Committee. Definition for sepsis and organ failure and guidelines for the innovative therapies in sepsis. Crit Care Med 1992;20:864-74 https://doi.org/10.1097/00003246-199206000-00025
  2. Cremer J, Martin M, Redl H. Systemic inflammatory response syndrome after cardic operation. Ann Thorac Surg 1996;61;1714-20
  3. Rangel-Frausto MS, Pittet D, Costigan M, Hwang T, Davis CS, Wenzel UP. The natural history of the systemic inflammatory response syndrome (SIRS). JAMA 1995;273;117-23.
  4. Beal Al, Cerra FB. Multiple organ failure syndrome in the 1990s. JAMA 1994;268;3452-5
  5. Berger D, Bolke E, Huegel H, et al. New aspects concerning the regulation of the postoperative acute phase reaction during cardiac surgery. Clinica Chimica Acta 1995;239;121-30
  6. Wan S, LeClerc JL, Vincent JL. Inflammatory response to cardiopulmonary bypass: mechanisms involved and possible therapeutic strategies. Chest 1997;112;676-92
  7. Ricardo LL, Marcela AD, Gustavo FB, et al. Methylene blue reduces mortality and morbidity in vasoplegic patients after cardiac surgery. Ann Thorac Surg 2004;77;496-9
  8. Park KH, Choi SC, Han IY, Choi KL, Choi KJ, Cho KH. Relationship between interleukin-6 production and inflammatory response during cardiopulmonary bypass. Korean J Thorac Cardiovasc Surg 2000;33;407-18.