Automatic Detection Method of the Region of Interest in the Measurement of Bone Mineral Density by Ultrasound Imaging

초음파 영상에 의한 골밀도 측정에서 관심영역의 자동 검출방법

  • 신정식 (부산대학교 지능기계공학과 대학원) ;
  • 안중환 (부산대학교 지능기계공학과 대학원) ;
  • 한은옥 (이화여자대학교 보건의료교육과) ;
  • 김형준 (경희대학교 동서의학대학원) ;
  • 한승무 (경희대학교 동서의학대학원)
  • Published : 2004.11.01

Abstract

In ultrasonic bone densitometry, the positioning of measurement site is decisive in precision and reproducibility. In this study, automatic Region of Interest (ROI) detection algorithm is suggested and adopted the method using the local minimum value by ultrasonic image. The preprocess before the local minimum method extracts out the bone area and calculates the geometrical information of bone. The developed ROI detection algorithm was applied to the clinical test for the subject of 305 female patients in the range of 22-88 years old. As the results, the accuracy of the algorithm was shown to be 98.3%. It was also found that bone density parameter was significantly correlated with age(r=0.85, p<0.0001).

Keywords

References

  1. Laugier, P., Fournier, B., Berger, G., 'Ultrasound Parametric Imaging of the Calcaneus: In Vivo Results with a New Device,' Calcif tissue Int, Vol. 58,pp.326-331, 1996 https://doi.org/10.1007/s002239900053
  2. Lanton, C.M., Palmer, S.B., Porter, R.W., 'The measurement of broadband ultrasonic attenuation in cancellous bone,' Eng. Med. 13, pp.89-91, 1984 https://doi.org/10.1243/EMED_JOUR_1984_013_022_02
  3. Cheng, S., Suominen, H., 'Comparison of ultrasound and bone mineral density assessment of the calcaneus with different regions of interest in healthy early menopausal women,' J. Clin. Densitom., Vol. 2, No.2,pp. 117-126, 1999 https://doi.org/10.1385/JCD:2:2:117
  4. Rosentall, L., Caminis, J., Tenehouse, A., 'Calcaneal ultrasonometry: response to treatment in comparison with dual x-ray absorptiometry measurements of the lumbar spine and femur,' Calcif. Tissue Int., Vol. 64, No.3, pp.200-204, 1999 https://doi.org/10.1007/s002239900602
  5. Iki, M., Kajita, E., Mitamura, S., 'Precision of quantitative ultrasound measurement of the heel bone and effects of ambient temperature on the parameters,' Osteoporosis Int., Vol.10, No.6, pp.462-467, 1999 https://doi.org/10.1007/s001980050255
  6. Chappard, C, Camus, E., Lefebvre, F., Guillot, G., Bittoun, J., Berger, G., Laugier, P., 'Evaluation of error bounds on calcaneal speed of sound caused by surrounding soft tissue,' J. Clin. Densitom., Vol. 3, No.2,pp. 121-131,2000 https://doi.org/10.1385/JCD:3:2:121
  7. Chappard, C., Berger, G., Roux, C., Laugier, P., 'Ultrasound measurement on the calcaneus: influence of immersion time and rotation of the foot,' Osteoporosis Int. 9, pp.318-326, 1999 https://doi.org/10.1007/s001980050154
  8. Han, S.M., Rho, J., 'Dependence of broadband ultrasound attenuation the anisotropy of elastic moduli in cancellous bone,' ImecE., Vol.212, 1-5, 1998
  9. Han, S.M., Davis, J., 'A comparison between the patella and the calcaneus in ultrasound velocity and attenuation as predictors of bone mineral density,' Physics in Medicine and Biology, pp.42 1-9, 1997 https://doi.org/10.1088/0031-9155/42/10/008
  10. Han, S.M., 'Ultrasound velocity and attenuation in relation to maximum trabecula stress in the patella,' Medical Engineering & Physics, Vol. 21, pp.541-546, 1999 https://doi.org/10.1016/S1350-4533(99)00077-6
  11. Brooke-Wavell, K., Jones, PR., Pye, D.W., 'Ultrasound and dual X-ray absorptiometry measurement of the calcaneus: influence of region of interest location,' Calcif. Tissue Int., Vol. 57, No.l, pp.20-24, 1995 https://doi.org/10.1007/BF00298991
  12. Lefebvre, F., Berger, G., Laugier, P., 'Automatic detection of the boundary of the calcaneus from ultrasound parametric images using an active contour model; clinical assessment,' IEEE Transactions on Medical Imaging, Vol. 17, No.l, pp.45-52, 1998 https://doi.org/10.1109/42.668693