Nutritional Sciences
- Volume 7 Issue 3
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- Pages.133-137
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- 2004
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- 1229-232X(pISSN)
The Anti- and Pro-oxidative Effects of Orally Administered Flavonoids in Normal Rats
- Park, Eun-Jeong (Research Institute, National Cancer Center, Department of Biotechnology, Korea University) ;
- Chee, Kew-Mahn (Department of Biotechnology, Korea University) ;
- Park, Moo-Young (Department of Food Science and Nutrition, Sangji University)
- Published : 2004.08.01
Abstract
The present study was designed to investigate the effects of genistein, daidzein, and quercetin on the antioxidative systems of normal rats. Male Sprague-Dawley rats were divided randomly into seven groups and treated with flavonoids at either 2 or 20 mg/day or through vehicle for four weeks. Lipid peroxidation in the liver was inhibited significantly following administration of quercetin. Genistein and daidzein did not have significant effects except in rats treated with 20mg daidzein/day. Genistein and daidzein treatment did not affect the content of