Current Status and Characteristics of Highly Pathogenic Avian Influenza

고병원성 가금인플루엔자의 최근 발생동향과 질병 특성

  • Kim, J.H. (National Veterinary Research and Quarantine Service) ;
  • Sung, H.W. (National Veterinary Research and Quarantine Service) ;
  • Kwon, Y.K. (National Veterinary Research and Quarantine Service) ;
  • Lee, Y.J. (National Veterinary Research and Quarantine Service) ;
  • Choi, J.G. (National Veterinary Research and Quarantine Service) ;
  • Cho, S.J. (National Veterinary Research and Quarantine Service) ;
  • Kim, M.C. (National Veterinary Research and Quarantine Service) ;
  • Lee, E.K. (National Veterinary Research and Quarantine Service) ;
  • Jang, H. (National Veterinary Research and Quarantine Service) ;
  • Wee, S.H. (National Veterinary Research and Quarantine Service) ;
  • Mo, I.P. (College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University) ;
  • Song, C.S. (College of Veterinary Medicine, Konkuk University) ;
  • Park, J.M. (National Veterinary Research and Quarantine Service)
  • 김재홍 (국립수의과학검역원) ;
  • 성환우 (국립수의과학검역원) ;
  • 권용국 (국립수의과학검역원) ;
  • 이윤정 (국립수의과학검역원) ;
  • 최준구 (국립수의과학검역원) ;
  • 조성준 (국립수의과학검역원) ;
  • 김민철 (국립수의과학검역원) ;
  • 이은경 (국립수의과학검역원) ;
  • 장환 (국립수의과학검역원) ;
  • 위성환 (국립수의과학검역원) ;
  • 모인필 (충북대학교 수의과대학) ;
  • 송창선 (건국대학교 수의과대학) ;
  • 박종명 (국립수의과학검역원)
  • Published : 2004.06.01

Abstract

Highly Pathogenic Avian Influenza (HPAI) is a very acute systemic disease in poultry, particularly in chickens and turkeys caused by HPAI viruses. An outbreak of HPAI caused by subtype H5N1, was first reported in a broiler breeder farm on December 10, 2003 in Korea, although there had been twenty one outbreaks of the disease reported in the world before. Since mid-December 2003, eight Asian countries have confirmed outbreaks of HPAI due to the same subtype. The outbreak has also resulted in at least twenty three fatal human cases in Vietnam and Thailand as of May 17, 2004 according to the WHO. Regarding the first outbreak of recent Asian HPAI, it has been suspected that some Asian countries with the exception of Korea and Japan veiled the fact of HPAI outbreaks since the last half of 2003, even though it was first reported in Korea. There have been total nineteen outbreaks of HPAI among chicken and duck farms in 10 provinces in Korea since Dec. 2003 and approximately 5,280,000 birds were slaughtered from 392 farms for eradication of the disease and preemptive culling. The origin of the H5Nl HPAI virus introduced into the country are unknown and still under epidemiological investigation. Current status of outbreaks and characteristics of HPAI will be reviewed and discussed on the basis of genetic, virological, clinicopathological, and ecological aspect, as well as future measures for surveillance and prevention of the disease in Korea.

Keywords

References

  1. Veterinary Microbiology v.74 A review of avian influenza in different bird species Alexander,D.J. https://doi.org/10.1016/S0378-1135(00)00160-7
  2. Proceedings of the Fifty International Symposium on Avain Influenza. Avian Diseases v.47 Report on Avian Invluenza in the eastern hemisphere during 1997-2002. Alexander,D.J.
  3. A review. Avian Pathology v.29 The avian influenza epidemic in Italy, 1999-2000 Capua,I.;Marangon,S. https://doi.org/10.1080/03079450050118403
  4. J Virology v.74 no.14 Continued circulation in China of highly pathogenic avian influenza viruses encoding the hemagglutinin gene associated with the 1997 H5N1 outbreak in poultry and humans Cauthen,A.N.;Swayne,D.E.;Schultz-Cherry,S.;Perdue,M.L.;Suarez,D.L. https://doi.org/10.1128/JVI.74.14.6592-6599.2000
  5. Virus taxonomr. Seventh report of the intermational committee on taxonomy of viruses Orthomyxoviridae Cox,N.J.;Fuller,F.;Kaverin,N.;Klenk,H.D.;Lamb,R.A.;Mahy,B.W.;McCauley,J.W.;Nakamura,K.;Palese,P.;Webster,R.G.;Van Regenmortel,M.H.(ed.);Fauquet,C.M.(ed.);Bishop,D.H.L.(ed.);Carstens,E.B.(ed.);Estes,M.K.(ed.);Lemon,S.M.(ed.);Maniloff,J.(ed.);Mayo,M.A.(ed.);McGeoch,D.J.(ed.);Pringle,C.R.(ed.);Wickner,R.B.(ed.)
  6. The use of Vaccination against Avian Influenza The Definition of Avian Influenza EU Scientific Committee on Animal Health and Animal Welfare
  7. Update on the Avian Influenza situation(As of 13/05/2004) no.Issue 14 FAO AIDE News FAO Avian Influenza Technical Task Force
  8. PNAS v.99 no.13 Emergence of multiple genotypes of H5N1 avian influenza viruses in Hong Kong SAR Guan,Y.;Peiris,J.S.M.;Lipatov,A.S.;Ellis,T.M.;Dyrting,K.C.;Krauss,S.;Zhang,L.J.;Webster,R.G.;Shortridge,K.F. https://doi.org/10.1073/pnas.132268999
  9. Virology v.267 Characterization of the pathogenicity of members of the newly established H9N2 influenza virus lineages in Asia Guo,Y.J.;Krauss,S.;Senne,D.A.;Mo,I.P.;Lo,K.S.;Xiong,X.P.;Norwood,M.;Shortridge,K.F.;Webster,R.G.;Guan,Y. https://doi.org/10.1006/viro.1999.0115
  10. Avian Pathology v.31 The control of H5 or H7 mildly pathogenic avian influenza: a role for inactivated vaccine Halvorson,D.A. https://doi.org/10.1080/03079450120106570
  11. J Virol v.74 no.14 Characterization of the influenza A virus gene pool in avain species in southern China: Was H6N1 a Derivative or a precursor of H5N1 Hoffmann,E.;Stech,J.;Leneva,I.;Krauss,S.;Scholtiss,C.;Chin,P.S.;Peiris,M.;Shortridge,K.F.;Webster,R.G.
  12. Clinical Microbiology Reviews v.14 no.1 Pandemic threat posed by avian influenza A viruses Horimoto,T.;Kawaoka,Y. https://doi.org/10.1128/CMR.14.1.129-149.2001
  13. Virology v.213 Origin and molecular changes associated with emergence of a highly pathogenic H5N2 influenza virus in Mexico Horimoto,T.;Rivera,E.;Pearson,J.;Senne,D.;Krauss,S.;Kawaoka,Y.;Webster,R.G. https://doi.org/10.1006/viro.1995.1562
  14. J Virol v.72 Molecular basis for the generation in pigs of influenza A viruses with pandemic potential Ito,T.;Nelson,J.;Couceiro,S.S.;Kelm,S.;Baum,L.G.;Krauss,S.;Castrucci,M.R.;Donatelli,I.;Kida,H.;Paulson,J.C.;Webster,R.G.;Kawaoka,Y.
  15. J Virology no.May Generation of a highly pathogenic avian influenza A virus from an avirulent field isolate by passaging in chickens Ito,T.;Goto,H.;Yamamoto,E.;Tanaka,H.;Takeuchi,M.;Kuwayama,M.;Kawaoka,Y.;Otsuki,K.
  16. Proceedings of the Fifty International Symposium on Avain Influenza. Avian Diseases v.47 The quest of influenza A viruses for new hosts Liu,M.;Guan,Y.;Peiris,M.;He,S.;Webby,R.J.;Perez,D.;Webster,R.G.
  17. J Medical Virology v.69 Pathogenicity and antigenicity of a new influenza A (H5N1) virus isolated from duck meat Lu,X.;Cho,D.;Hall,H.;Rowe,T.;Sung,H.;Kim,W.;Kang,C.;Mo,I.;Cox,N.;Klimov,A.;Katz,J. https://doi.org/10.1002/jmv.10344
  18. Proc. 4th International Symposium on Avian Influenza An occurrence of non-highly pathogenic avian influenza in Korea Mo,I.P.;Song,C.S.;Kim,K.S.;Rhee,J.C.
  19. Manual of standards Diagnostic Tests and Vaccines Highly pathogenic avian influenza OIE Code Commission
  20. C. Hannoun, Editor, Options for the Control of Influenza, The role of swine in the origin of pandemic influenza Scholtissek,C.;Schultz,U.;Ludwig,S.;Fitch,W.M.
  21. Avian Dis v.40 Survey of the hemagglutinin (HA) cleavage site sequence of H5 and H7 avian influenza viruses; amino acid sequence at the HA cleavage site as a marker of pathogenicity potential Senne,D.A.;Panigraphy,B.;Kawaoka,Y.;Pearson,J.E.;Suss,J.;Lipkind,M.;Kida,H.;Webster,R.G. https://doi.org/10.2307/1592241
  22. Proceeding of the 3rd International Symposium on Avian Influenza Live poultry markets: a missing link in the epidemiology of avian influenza Senne,D.A.;Pearson,J.E.;Panigraphy,B.
  23. Bulletin of the World Health Organization v.60 no.1 Avian influenza A viruses of southern China and Hong Kong: ecological aspects and implications for man Shortridge,K.F.
  24. Vet Microbiol v.74 Interspecies transmission of Influenza viruses: H5N1 virus and a Hong Kong SAR perspective Shortridge,K.F.;Gao,P.;Guan,Y.;Ito,T.;Kawaoka,Y.;Markwell,D.;Takada,A.;Webster,R.G. https://doi.org/10.1016/S0378-1135(00)00174-7
  25. Proceedings of the Fifty International Symposium on Avain Influenza. Avain Diseases v.47 Avian influenza in Hong Kong 1997-2002 Sims,L.D.;Ellis,T.M.;Liu,K.K.;Dyrting,K.;Wong,H.;Peiris,M.;Guan,Y.;Shortridge,K.F.
  26. Proceedings of the 4th International Symposium on AI. Athens, Georgia Ecology and epidemiology of AIVs in wild bird populations Stallknecht,D.E.
  27. Vet Res Commun v.12 Host range of AIV in free-living birds Stallknecht,D.E.;Shame,S.M. https://doi.org/10.1007/BF00362792
  28. Diseases of Poultry(11th ed.) Influenza Swayne,D.E.;Halvorson,D.A.
  29. J. Virol v.76 no.12 Characterization of a highly pathogenic H5N1 avian influenza A virus isolated from duck meat Tumpey,T.M.;Suarez,D.;Perkins,L.E.;Senne,D.A.;Lee,J.E.;Lee,Y.J.;Mo,I.P.;Sung,H.W.;Swayne,D.E. https://doi.org/10.1128/JVI.76.12.6344-6355.2002
  30. Vaccine v.20 The importance of animal influenza for human disease Webster,R.G. https://doi.org/10.1016/S0264-410X(02)00123-8
  31. Microbiol Rev v.56 Evolution and ecology of influenza A viruses Webster,R.G.;Bean,W.J.;Gorman,O.T.;Chambers,T.M.;Kawaoka,Y.
  32. J Virol no.April Rapid evolution op H5N1 influenza viruses in chickens in Hong Kong Zhou,N.N.;Shortridge,K.F.;Class,E.C.J.;Krauss,S.L.;Webster,R.G.
  33. 환경통계연감 no.16 환경부