Journal of Life Science (생명과학회지)

Korean Society of Life Science (한국생명과학회)
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Improved Astaxanthin Production of Xanthophyllomyces dendrorhous with Carotenogenesis Stimulating Factors

Carotenogenesis의 생성 자극 인자를 이용한 Xanthophyllomyces dendrorhous에 의한 astaxanthin 산물의 증가

  • Xu, Bao-Jun (The Pharmaceutical Institute, Dalian University) ;
  • Sung, Chang-Keun (Department of Food Science and Technology, College of Agriculture and Biotechnology, Chungnam National University) ;
  • Li, Chang-Tian (Department of Food Science and Technology, College of Agriculture and Biotechnology, Chungnam National University) ;
  • Mo, Eun-Kyoung (Biotechnology Research Institute, Dbio Inc.,)
  • Published : 2004.06.01
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Abstract

To improve biomass and astaxanthin production by wild-type Xanthophyllomyces dendrorhous simultaneously in shake flask culture, physical factors, nutritional factors and carotenogenesis stimulating factors affecting astaxanthin production were studied on base of HPLC quantitative analysis. The results suggested that carotenogenesis precursor composition acetic acid, mevalonic acid, tomato extract, and carrot extract could increase the productivity of astaxanthin markedly based on the optimized temperature, initial pH value, carbon and nitrogen sources conditions.

야생 균주 Xanthophyllomyces dendrorhous으로부터 biomass와 astaxanthin 산물을 증가시키기 위해 shake flask배양 조건에서 astaxanthin산물에 영향을 미치는 물리적 인자, 영양 인자와 Carotenogenesis의 생성 자극 인자에 대한 연구를 HPLC분석 방법을 이용하여 수행하였다. 최적에 온도, 초기 pH값, 탄소와 질소 공급 조건에서 Carotenogenesis의 선구 물질인 acetic 산, mevalonic 산, 토마토 추출물과 당근 추출물은 astaxanthin 생산을 상당히 증가시킬 수 있었다.

Keywords

References

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