Archives of Pharmacal Research

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Flavonoids of Crotalaria sessiliflora

  • Yoo, Hun-Sung (College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University) ;
  • Lee, Ji-Suk (East-West Medical Research Institute, Kyung Hee University) ;
  • Kim, Chul-Young (College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University) ;
  • Kim, Jin-Woong (College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University)
  • Published : 2004.05.01
Download PDF
⟨ Previous Next ⟩

Abstract

Phytochemical investigation of the whole plants of Grata/aria sessiliflora L. led to the isolation of four flavonoids. The structures of these compounds were identified as 2',4',5,7-tetrahydroxy-isoflavone (1), 2',4',7-trihydroxyisoflavone (2), 4',7-dihydroxyflavone (3), and isovitexin (4) using spectroscopic analysis. Among these, compounds 2, and 3 have not been reported from Crotalaria species, whereas compounds 1, and 4 were reported from this plant for the first time.

Keywords

References

  1. Agrawal, P. K. and Bansal, M. C., Isoflavonoids, Agrawal, P. K. (Eds.). In Carbon-13 NMR of Flavonoids. Elsevier, Amsterdam, pp. 183-235 (1989a)
  2. Agrawal, P. K. and Bansal, M. C., Flavonoid glycosides, Agrawal, P. K. (Eds.). In Carbon-13 NMR of Flavonoids. Elsevier, Amsterdam, pp. 283-364 (1989b)
  3. Biggs, R., Post-infectional compounds from the French bean Phaseolus vulgaris: Isolation and identification of genistein and 2',4',5,7-tetrahydroxyisoflavone. Aust. J. Chem., 28, 1389-1392 (1975) https://doi.org/10.1071/CH9751389
  4. Huang, L.,Wu, K.-M., Xue, Z., Cheng, J.-C., Xu, L.-Z., Xu, S.-P., and Xi, Y.-G., The isolation of antitumor active principle of Cratalaria sessiliflora and synthesis of its derivatives (authors transl). Yao Xue Xue Bao (Acta Pharmaceutica Sinica), 15, 278-283 (1980). (cf. Chem. Abstr., 95, 43427,1981)
  5. Kim, T. J., Korean Resources Plants, Vol II, Seoul National University Press, Seoul, p.251 (1996)
  6. Lane, G. A. and Newman, R. H., Isoflavones from Lupinus angustifolius root Phytochemistry, 26, 295-300 (1987) https://doi.org/10.1016/S0031-9422(00)81531-9
  7. Markham, K. R., Techniques of Flavonoid Identification, AcademicPress, London, pp 86-90 (1982)
  8. Markham, K. R. and Chari, V. M., Carbon-13 NMR spectroscopy of flavonoids, Harborne, J.B. and Mabry, T.J. (Eds.). In The Flavonoids: Advances in Research. Chapman & Hall, London, pp. 129-132 (1982)
  9. Markham, K. R. and Geiger, H., $^{1}H$ nuclear magnetic resonance spectroscopy of flavonoids and their glycosides in hexadeuterodimethylsulfoxide. Harborne, J.B. (Eds.). In The Flavonoids: Advances in Research Since 1986. Chapman & Hall, London, pp. 441-497 (1994)
  10. Roder, E., Liang, X. T., and Kabus, K.J., Pyrrolizidine alkaloids from the seeds of Crotalaria sessiliflora. Planta Med., 58, 283 (1992) https://doi.org/10.1055/s-2006-961458
  11. Shirataki, Y., Yokoe, I., and Komatsu, M., Two new flavone glycosides from the roots of Sophora subprostrata. J. Nat. Prod., 49, 645-649 (1986) https://doi.org/10.1021/np50046a014
  12. Woodward, M. D., Phaseollin formation and metabolism in Phaseolus vulgaris. Phytochemistry, 19, 921-927 (1980) https://doi.org/10.1016/0031-9422(80)85139-9