Iron, Copper and Zinc Levels in Human Milk and Estimated Intake of the Minerals by Breast-Fed Infants during the Early Lactation

수유 초기 모유 중 철, 구리, 아연의 함량과 영아의 섭취량 추정

  • 김을상 (단국대학교 식품영양학과) ;
  • 조금호 (단국대학교 식품영양학과)
  • Published : 2004.02.01

Abstract

The objectives of the present study were to measure the content of iron, copper and zinc in human milk and to estimate the intake of iron, copper and zinc of breast-fed infants during the early period of lactation. Twenty-five lactating women who delivered in a hospital in Seoul volunteered for the study. Milk samples were collected at day 2, 3, 4, 5, 6, 7, 15 and 30 postpartum. The contents of iron, copper and zinc were determined using the atomic absorption spectrophotometer after wet digestion. The intakes of iron, copper and zinc of infants were estimated by multiplization with the infant milk intake reported in our laboratory. The content of iron was 0.58 $\mu\textrm{g}$/g in colostrum, 0.48 $\mu\textrm{g}$/g in transitional milk and 0.39 $\mu\textrm{g}$/g in mature milk while the estimated iron intake of infants was 271, 255 and 259 $\mu\textrm{g}$/day, respectively. The content of copper in the milk was 0.45 $\mu\textrm{g}$/g in colostrum, 0.43 $\mu\textrm{g}$/g in transitional milk and 0.33 $\mu\textrm{g}$/g in mature milk while the estimated copper intake of infants was 210, 229 and 220 $\mu\textrm{g}$/day, respectively. The content of zinc in the milk was 5.24 $\mu\textrm{g}$/g in colostrum, 3.70 $\mu\textrm{g}$/g in transitional milk, 2.93 $\mu\textrm{g}$/g in mature milk while the estimated zinc intake of infants was 2452, 1968, and 1949 $\mu\textrm{g}$/day, respectively. These results suggest that copper and zinc intake of infants are met to RDA but iron is not.

Keywords

References

  1. Korean J Nutrition v.28 Nutritional needs and assessment of normal infants Ahn,H.S.
  2. Korean J Nutrition v.29 Nutrient intakes of infants according to feeding pater at 2 month age Bai,H.S.;Lee,D.H.;Ahn,H.S.
  3. Wld Rew Nutr Diet v.36 biochemical aspects of human milk-comparison with bovine milk Blance,B.
  4. Fed Proc v.43 Milk and mineral intake of 45 exclusively breast-fed infants Butte,N.F.;Garza,C.;Smith,E.O.B.;Nichols,B.L.
  5. Am J Clin Nutr v.45 Mcro- and trace-mineral intakes of exclusively breast-fed infants Butte,N.F.;Garza,C.;Smith,E.O.B.;Wils,C.;Nichols,B.L.
  6. Am J Clin Nutr v.41 Studies in human lactation: zinc, copper, manganaseand chromium in human milk in the first milk of lactation Casey,C.E.;Hambridge,K.M.;Neville,M.C.
  7. Am J Clin Nutr v.49 Studies in human lactation: secretion of zinc, copper and manganese in human milk Casey,C.E.;Neville,M.C.;Hambridge,K.M.
  8. Korean J Sanitat v.3 Studies on the concentrations of essential trace elements in breast milk Cho,Y.S.;Kim,D.S.
  9. Korean J Community Nutrition v.4 A longitudinal study of the iron and zinc intakes of Korean infants from 1 to 3 months-breast-fed vs Formula-fed infants Choi,K.;Mo,S.;Choi,H.;Koo,J.
  10. Korean J Nutrition v.24 A study on iron, zinc and copper contents in human milk and trace element intakes of breast-fed infants Choi,M.G.;Ahn,H.S.;Moon,S.J.;Lee,M.J.
  11. J Pediatr Gastroenterol Nutr v.2 Calcium, phosphorus and magnesium contents of human milk during early lactation Feeley,R.M.;Eitemniuller,R.R.;Jones,J.B.;Banhart,H.
  12. J Nutr v.115 Inorganic constituents of breast milk from vegetarian and nonvegetarian vomen: Relationships with each other and with organic constituents Finley,D.A.;Lonnerdal,B.;Dewey,K.G.;Grivetti,L.E.
  13. J Pediatr v.96 Iron in human milk Franson,G.B.;Lonnerdal,B.
  14. Pediatrics v.28 A study on the trace metal content in breast milk of Korean Han,S.W.;Cho,Y.S.;Cho,T.W.;Choi,K.S.;Jung,S.W.;Kim,D.S.;Cho,J.H.;Sim,E.K.
  15. Am J Clin Nutr v.47 Zinc,calcium, and magnesium concentrations in milk from American and Egyptian women throughout the first 6 months of lactation Karra,M.V.;Kirksey,A.;Galal,O.;Bassily,N.S.;Harrison,G.G.;Jerome,N.W.
  16. Korean J Nutrition v.32 A longitudinal study on zinc secretion of lactating women and zinc intake of breast-fed infants Kim,E.S.;Keum,H.K.
  17. Korean J Nutrition v.35 A longitudinal study on energy, protein, fat and lactose intakes of breast-fed infants Kim,E.S.;Lee,J.S.
  18. Report of NIER Korea v.9 Zinc and copper concentrations in human milk. Korean lactating women Kim,H.Y.;Ahn,H.Y.;Choi,Y.Y.;Hwang,T.J.;Sohn,C.
  19. Am J Clin Nutr v.41 The effects of a dietary zinc supplement during lactation on longitudinal changes in maternal zinc status and milk zinc concentrations Krebs,N.F.;Hambidge,K.M.;Jacbs,M.A.;Rasbach,J.O.
  20. Korean J Nutrition v.24 A longitudinal study on human milk volume and lactational pattern Lee,J.S.;Kim,E.S.
  21. Korean J Nutrition v.31 Study on vitamin A intake of breast-fed infants dyring the first 5 months of lactation Lee,J.S.;Kim,E.S.
  22. Korean J Nutrition v.33 Study on zinc and copper intakes of breast-fed infants Lee,J.S.;Lee,Y.N.;Kim,E.S.
  23. Korean J Nutrition v.30 Changes on calcium, phosphorous and magnesium content of breast milk during lactation Lee,Y.N.;Lee,J.S.;Kim,E.S.
  24. Korean J Nutrition v.28 A comparative study on the composition of preterm and fullterm human milk in colostrum Lee,Y.W.;Moon,S.J.;Lee,M.J.;Moon,H.N.;Hong,S.J.
  25. Ann Rev Nutr v.1 Milk trace elments Lonnerdal,B.
  26. J Pediatr Gastroenterol Nutr v.6 Measurement of milk transfer from mother to breast-fed infant Neville,M.C.
  27. J Pediatrics v.92 Immunologic aspects of human colostrum and milk Ogra,S.S.;Ogra,P.L.
  28. Am J Clin Nutr v.29 Copper, iron and zinc contents of mature human milk Picciano,M.F.;Guthrie,M.A.
  29. Pediatric Research v.19 Exclusively breast-fed healthy infants grow slower than reference infants Salmenpera,L.;Perheentupa,J.;Siimes,M.A.
  30. Korean J Nutrition v.26 A longitudinal study on human milk intake in exclusively breast-fed infants Seol,M.Y.;Kim,E.S.;Keum,H.K.
  31. Modern nutrition in health and disease(8th eds.) Shils,M.E.;Olson,J.A.;Shike,M.
  32. Acta Paediatr Scand v.68 Breast milk iron-A declining concentration during the course of lactation Siimes,M.A.;Vuori,E.;Kuitunen,P.
  33. Br J Nutr v.63 Breast milk zinc and copper concentrations in Bangladesh Simmer,K.;Ahmed,S.;Carlsson,L.;Thompson,R.P.H.
  34. Physiol Rev v.19 The mineral metabolism of normal infants Stearns,G.
  35. Recommended Dietary Allowances for Koreans(KRDA)(7th ed.) The Korean Nutrition Society
  36. Am J Clin Nutr v.32 Longitudinal changes in the mineral content of human milk Vaughan,L.A.;Weber,C.W.;Kemberling,S.R.
  37. Acta Paediatr Scand v.68 The concentrations of copper and zinc in human milk Vuori,E.;Kuitunen,P.
  38. Food and Nutrition Bulletin Supplement v.6 Maternal diet, breast-feeding capacity, and lactational infertility Whitehead,R.G.
  39. JAMA v.175 Differences between cow's and human milk Williams,H.H.
  40. Nutrition in pregnancy and lactation(5th ed.) Worthington-Roberts,B.S.;Williams,S.R.
  41. Korean J Nutrition v.28 A study on the contents of selenium and zinc in human milk Yang,H.R.;Keum,H.K.;Kim,E.S.