Archives of Pharmacal Research

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Quality Evaluation of Alismatis Rhizoma by High Performance Liquid Chromatography

  • Published : 2004.04.01
Download PDF
⟨ Previous Next ⟩

Abstract

The quality of Alismatis Rhizoma was evaluated by reversed-phase high performance liquid chromatographic method. Alisol B 23-acetate was used as a standard marker for evaluation. This component was fully separated from the other components in the plant extracts on a ODS column. Identifcation of alisol B 23-acetate was carried out by comparing the LC/MS spectrum of separated peak from the extract with that of standard. Alisol B 23-acetate contents in Alismatis Rhizoma obtained from several herbal markets were varied from $0. 15\%$ to $0.56\%$.

Keywords

References

  1. Bae, K., Medicinal plants of Korea, Kyohaksa, Seoul, p. 519 (2000)
  2. Fukuyama, Y., Geng, P., Wang, R., Yamada, Y., and Nakagawa, K., 11-Deoxyalisol C and alisol D: New protostane-type triterpenoides from Alisma plantago-aquatica. Planta Med., 54,445-447 (1998) https://doi.org/10.1055/s-2006-962495
  3. Lee, S. M., Kho, Y. H., Min, B. S., Kim, J. H., Na, M. K., Kang, S. J., Maeng, H. Y., and Bae, K. H., Cytotoxic triterpenoides from Alismatis Rhizoma. Arch. Pharm. Res., 24, 524-526 (2001) https://doi.org/10.1007/BF02975158
  4. Lee, S. M., Kim, J. H., Zhang, Y., An, R. B., Min, B. S., Jong, H. O., and Lee, H. K., Anti-complementary activity of protostane-type triterpenes from Alismatis Rhizoma. Arch. Pharm. Res., 26, 463-465 (2003) https://doi.org/10.1007/BF02976863
  5. Matsuda, H., Tomohiro, N., Yoshikawa, M., and Kubo, M., Anticomplementary activities of methanol extract and terpene components from Alismatis Rhizoma. Biol. Pharm. Bull., 21, 1317-1384 (1998). https://doi.org/10.1248/bpb.21.1317
  6. Murata, T., Shinohara, M., and Miyamoto, M., Biological active triterpenes of Alismatis Rhizoma. Chem. Pharm. Bull., 18, 1369-1384 (1970) https://doi.org/10.1248/cpb.18.1369
  7. Yamaguchi, K., Ida, Y., Satoh, Y., Nakajima, Y., and Shoji, Z., A kaurane derivative isolated from Alisma oriental. Acta. Crystallogr., Sect. C: Cryst. Struct. Commun., 50, 738 (1994) https://doi.org/10.1107/S010827019301220X
  8. Yamahara, J., Kobayashi, G., Iwamoto, M., Matsuda, H., and Frjimura, H., The effect of alisol isolated from Alismatis Rhizoma on experimental hypertensive models in rat. Phytother. Res., 3, 57-62 (1989) https://doi.org/10.1002/ptr.2650030205
  9. Yoshikawa, M., Hatakeyama, S., Tanaka, N., Fukuda, Y., Murakami, N., and Yamahara, J., Orientalols A, B, and C, sesquiterpene constituents from Chinese Alismatis Rhizoma. Chem. Pharm. Bull., 40, 2582-2584 (1992) https://doi.org/10.1248/cpb.40.2582
  10. Yoshikawa, M., Yamaguchi, S., Matsuda, H., Kohda, Y., Ishikawa, H., Tanaka, N., Yamahara, J., and Murakami, N., Crude drug from aquatic plants. IV. On the constituents of Alismatis Rhizoma. Chem. Pharm. Bull., 42, 1813-1816 (1994a) https://doi.org/10.1248/cpb.42.1813
  11. Yoshikawa, M., Yamaguchi, S., Chatani, N., Nishino, Y., Matsuoka, T., Yamahara, J., Murakami, N., Matsuda, H., Kubo, M., Crude drugs from aquatic plants. III. Quantitative analysis of triterpene constituents in Alismatis Rhizoma by means of high-performance liquid chromatography on the chemical change of the constituents during Alismatis Rhizoma processing. Yakugaku Zasshi, 114,241-247 (1994b) https://doi.org/10.1248/yakushi1947.114.4_241