Korean Journal of Bronchoesophagology (대한기관식도과학회지)
- Volume 10 Issue 2
- /
- Pages.22-27
- /
- 2004
- /
- 1226-0916(pISSN)
The Therapeutic Effects of Ranitidine in Gastroesophageal Disease with Laryngopharyngeal Reflux (LPR) symptoms.
위식도 역류성질환 관련 인후두역류(Laryngopharyngeal Refulx : LPR)증상을 호소하는 환자에서의 라니티딘의 치료효과 연구
- Chang, H.S. (Department of Otorhinolaryngology, Soonchunhyang Univ.,) ;
- Ko, Y.W. (Soonchunhyang Univ.,) ;
-
Kim, K.H.
(Seoul National Univ.,)
;
-
Kim, Y.M.
(Catholic Univ.,)
;
-
Kim, S.Y.
(Ulsan Univ.,)
;
- Kim, Y.M. (Inha Univ.,) ;
- Do, M.Y. (Chosun Univ.,) ;
- Beak, C.H. (Sungkyunkwan Univ.,) ;
- Ahn, S.H. (Seoul National Univ.,) ;
- Eom, J.W. (Busan Paik Hosp., Inje Univ.,) ;
- Yang, H.S. (Chungang Univ.,) ;
- Woo, H.Y. (Sanggye Paik Hosp., Inje Univ.,) ;
- Lee, H.S. (Hanyang Univ.,)
- 장혁순 (순천향대학교 의과대학 이비인후과교실) ;
- 고윤우 (순천향의대) ;
-
김광현
(서울의대)
;
-
김민식
(가톨릭의대)
;
-
김상윤
(울산의대)
;
- 김영모 (인하의대) ;
- 도남용 (조선의대) ;
- 백정환 (성균관의대) ;
- 안순현 (서울의대) ;
- 엄재욱 (인제의대 부산백병원) ;
- 양훈식 (중앙의대) ;
- 우훈영 (인제의대 상계백병원) ;
- 이형석 (한양의대)
- Published : 2004.12.01
Abstract
Background : LPRD(Laryngopharyngeal reflux disease) gives rise to inflammatory change in the pharyngolaryngeal tissue with various otolaryngologic symptoms. Ranitidine, histamine H2receptor antagonists, are currently used as therapeutic medications. However, the efficacy of Ranitidine on LPRD has not been proven yet. Objectives : We intended to analyze the efficacy of the Ranitidine on LPRD. Materials :md Methods : In 20 multicenter, 607 patients with LPR(laryngopharyngeal reflux) symptom were observed to evaluate their symptoms and laryngoscopic findings after 4 weeks, 8 weeks, and 12 weeks of treatment of Ranitidine. Results : The symptom of LPR including globus sensation, sore throat hoarseness, regurgitatioin are improved after 4 weeks