Two Cases of Primary Small Cell Carcinomas of the Stomach

원발성 위 소세포암 2예

  • Seo Yun-Seock (Departments of Surgery Seoul National University College of Medicine) ;
  • Park Do Joong (Departments of Surgery and Cancer Research Institute Seoul National University College of Medicine) ;
  • Lee Hyuk-Joon (Departments of Surgery and Cancer Research Institute Seoul National University College of Medicine) ;
  • Cho Soo Youn (Departments of and Pathology Seoul National University College of Medicine) ;
  • Kim Woo Ho (Departments of Pathology, and Cancer Research Institute Seoul National University College of Medicine) ;
  • Park Seong Hoe (Departments of and Pathology Seoul National University College of Medicine) ;
  • Yang Han-Kwang (Departments of Surgery and Cancer Research Institute Seoul National University College of Medicine) ;
  • Lee Kuhn Uk (Departments of Surgery Seoul National University College of Medicine) ;
  • Choe Kuk Jin (Departments of Surgery Seoul National University College of Medicine)
  • 서윤석 (서울대학교 의과대학 외과학교실) ;
  • 박도중 (서울대학교 의과대학 외과학교실 및 암연구소) ;
  • 이혁준 (서울대학교 의과대학 외과학교실 및 암연구소) ;
  • 조수연 (서울대학교 의과대학 병리학교실) ;
  • 김우호 (서울대학교 의과대학 병리학교실 및 암연구소) ;
  • 박성희 (서울대학교 의과대학 병리학교실) ;
  • 양한광 (서울대학교 의과대학 외과학교실 및 암연구소) ;
  • 이건욱 (서울대학교 의과대학 외과학교실) ;
  • 최국진 (서울대학교 의과대학 외과학교실)
  • Published : 2004.09.01

Abstract

Primary small-cell carcinomas of the stomach are rare and aggressive malignancies with poor survival rates. Preoperative diagnosis is difficult and a standard treatment is not yet established. We have recently experienced two cases of a primary small-cell carcinoma of the stomach. The first case was a 65-year-old man with epigastric soreness. Endoscopic biopsy showed an adenocarcinoma. He underwent a radical subtotal gastrectomy with D2 lymph-node dissection. Pathology revealed a collision tumor of a smallcell carcinoma and an adenocarcinoma with submucosal invasion and with metastasis in 20 out of 48 lymph nodes (T1N3M0). The second case was a 64-year-old man with epigastric soreness. Endoscopic biopsy revealed a small-cell carcinoma. There was no evidence of a primary tumor in the lung. A radical subtotal gastrectomy with D2 lymph-node dissection was performed. Pathology showed a pure smallcell carcinoma with proper muscle invasion and with metastasis in 1 out of 36 lymph nodes (T2aN1M0).

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