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Functional bioactivity of Opuntia species

  • Shin, Tae-Kyun (Department of Veterinary Medicine, Cheju National University) ;
  • Wie, Myung-Bok (Department of Veterinary Medicine, Kangwon National University) ;
  • Lee, Nam-Ho (Department of Biochemistry, Cheju National University) ;
  • Lee, Du-Sik (Department of Veterinary Medicine, Cheju National University) ;
  • Son, Won-Geun (Department of Veterinary Medicine, Cheju National University) ;
  • Park, Dal-Soo (Department of Veterinary Medicine, Cheju National University) ;
  • Ahn, Mee-Jung (Department of Veterinary Medicine, Cheju National University) ;
  • Go, Gyung-Min (Provincial Fisheries Resources Research Institute)
  • Published : 2004.12.30

Abstract

Cacti of the genus Opuntia, which are widely distributed throughout Latin America, South Africa, the Mediterranean, and Korea, have been used not only as ornamental plants but also for their medicinal value. For example, Opuntia spp. have traditionally been used as hypoglycemic plants for treating diabetes mellitus. In this article, we review published papers dealing with the biological and medicinal properties of Opuntia spp.

Keywords

References

  1. Ahmad A, Davies J, Randall S, Skinner GR (1996) Antiviral properties of extract of Opuntia streptacantha. Antiviral Res. 30,75-85. https://doi.org/10.1016/0166-3542(95)00839-X
  2. Aires V, Adote S, Hichami A, Moutairou K, Boustani ES, Khan NA. (2004) Modulation of intracellular calcium concentrations and T cell activation by prickly pear polyphenols. Mol. Cell.Biochem. 260, 103-110. https://doi.org/10.1023/B:MCBI.0000026061.57326.28
  3. Baik SK, Kim HY, Yang SD, Song CW, Shin T, Han SS. (1999) The effects of Opuntia ficus-indica fruit powder on antioxidant parameters in senescence-accelerated mouse (SAM). Kor. J. Gerontol. 9,70-77.
  4. Budinsky A, Wolfram R, Oguogho A, Efthimiou Y, Stamatopoulos Y, Sinzinger H. (2001) Regular ingestion of opuntia robusta lowers oxidation injury. Prostaglandins Leukot Essent Fatty Acids 65, 45-50. https://doi.org/10.1054/plef.2001.0287
  5. Butera D, Tesoriere L, Di Gaudio F, Bongiorno A, Allegra M, Pintaudi AM, Kohen R, Livrea MA.(2002) Antioxidant activities of Sicilian prickly pear (Opuntia ficus indica) fruit extracts and reducing properties of its betalains: betanin and mdicaxanthin. J. Agric. Food Chem. 50, 6895-6901. https://doi.org/10.1021/jf025696p
  6. Dok-Go H, Lee KH, Kim HJ, Lee EH, Lee J, Song YS, Lee YH Jin C, Lee YS, Cho J. (2003) Neuroprotective effects of antioxidative flavonoids, quercetin, (+)-dihydroquercetin and quercetin 3-methyl ether, isolated from Opuntia ficus-indica var. saboten. Brain Res. 965,130-136. https://doi.org/10.1016/S0006-8993(02)04150-1
  7. El Kossori RL, Villaume C, El Boustani E, Sauvaire Y, Mejean L. (1998) Composition of pulp, skin and seeds of prickly pears fruit (Opuntia ficus indica sp.). Plant Foods Hum. Nutr. 52, 263-270. https://doi.org/10.1023/A:1008000232406
  8. Fernandez ML, Lin EC, Trejo A, McNamara DJ. (1994) Prickly pear (Opuntia sp.) pectin alters hepatic cholesterol metabolism without affecting cholesterol absorption in guinea pigs fed a hypercholesterolemic diet. J. Nutr. 124,817-824.
  9. Frati AC, Xilotl Diaz N, Altamirano P, Ariza R, Lopez-Ledesma R. (1991) The effect of two sequential doses of Opuntia streptacantha upon glycemia. Arch. Invest. Med. (Mex). 22,333-336.
  10. Frati-Munari AC, Gordillo BE, Altarnirano P, Ariza CR. (1988) Hypoglycemic effect of Opuntia streptacantha Lemaire in NTDDM Diabetes Care 11, 63-66. https://doi.org/10.2337/diacare.11.1.63
  11. Frati-Munari AC, Licona-Quesada R, Araiza-Andraca CR, Lopez-Ledesma R, Chavez-Negrete A. (1990) Activity of Opuntia streptacantha in healthy individuals with induced hyperglycemia. Arch. Invest. Med. 21,99-102.
  12. Galati EM, Mondello MR, Giuffrida D, Dugo G, Miceli N, Pergolizzi S, Taviano MF. (2003) Chemical characterization and biological effects of Sicilian Opuntia ficus indica (L) mill. Fruit juice: antioxidant and antiulcerogenic activity. J. Agric. Food Chem. 51,4903-4908. https://doi.org/10.1021/jf030123d
  13. Galati EM, Monforte MT, Tripodo MM d'Aquino A, Mondello MR. (2001) Anti-ulcer activity of Opuntia ficus indica (L.) Mill. (Cactaceae): ultrastructural study. J. Ethnopharmacol. 76,1-9. https://doi.org/10.1016/S0378-8741(01)00196-9
  14. Galati EM, Pergolizzi S, Miceli N, Monforte MT, Tripodo MM (2002) Study on the increment of the production of gastric mucus in rats treated with Opuntia ficus indica (L.) Mill, cladodes. J. Ethnopharmacol. 83,229-233. https://doi.org/10.1016/S0378-8741(02)00243-X
  15. Gurrieri S, Miceli L, Lanza CM, Tomaselli F, Bonomo RP, Rizzarelli E. (2000) Chemical characterization of Sicilian prickly pear (Opuntia ficus indica) and perspectives for the storage of its juice. J. Agric. Food Chem. 48,5424-5431. https://doi.org/10.1021/jf9907844
  16. Ha HJ, Kwon YS, Park SM Shin TK, Park JH, Kim HC, Kwon MS, Wie MB. (2003) Quercetin attenuates oxygen-glucose deprivation- and excitotoxin-induced neurotoxicity in primary cortical cell cultures. Biol. Pharm. Bull. 26,544-546. https://doi.org/10.1248/bpb.26.544
  17. Han YN, Choo Y, Lee YC, Moon YI, Kim SD, Choi JW. (2001) Monoamine oxidase B inhibitors from the fruit of Opuntia ficus-indica var. saboten. Arch. Pharm. Res. 24,51-54. https://doi.org/10.1007/BF02976493
  18. Heo SD, Park DS, Go GM, Kim MG, Son WG, Lee DS, Shin T. (2003) Antibacterial effect of Opuntia ficus-indica fermentation in cultured Olive Rounder, Paralichthys olivaceus. Kor. J. Vet. Public Health 27,143-147.
  19. Ibanez-Camacho R, Roman-Ramos R. (1979) Hypoglycemic effect of Opuntia cactus. Arch. Invest. Med. (Mexico) 10,223-230.
  20. Ibanez-Camacho R, Meckes-Lozoya M, Mellado-Campos V. (1983) The hypoglucemic effect of Opuntia streptacantha studied in different animal experimental models. J. Ethnopharmacol. 7, 175-181. https://doi.org/10.1016/0378-8741(83)90019-3
  21. Jeong SJ, Jun KY, Kang TH, Ko EB, Kim YC. (1999) Havonoids from the fruit of Opuntia ficus-indica var. saboten. Kor. J. Pharmacogn. 30,84-97.
  22. Kang MS, Kang JS. (2001) Hypocholesterolemic effect of tangerine pulp, sea tangle, or prickly perat cactus on lipid level, intestinal cholesterol absorption, platelet aggregation and liver tissue in hypercholesterolemic rats. Kor. J. Nutr. 34, 141-149.
  23. Kim JH. (2002) Opuntia ficus-indica protects against neuronal damage in gerbil ischemia and oxygen-glucose deprivation-induced neurotoxicity in cortical cultures. A Thesis for the Degree of Master of Veterinary Science, Cheju National University Graduate School, Jeju, Korea.
  24. Kuti JO. (2004) Antioxidant compounds from four Opuntia cactus pear fruit varieties. Food Chemistry 85,527-533. https://doi.org/10.1016/S0308-8146(03)00184-5
  25. Lee EH, Kim HJ, Song YS, Jin C, Lee KT, Cho J, Lee YS. (2003) Constituents of the stems and fruits of Opuntia ficus-indica var saboten. Arch. Pharm. Res. 26, 1018-1023. https://doi.org/10.1007/BF02994752
  26. Lee EB, Hyun JE, Li da W, Moon YI. (2002) Effects of Opuntia ficus-indica var. Saboten stem on gastric damages in rats. Arch. Pharm. Res. 25, 67-70. https://doi.org/10.1007/BF02975264
  27. Loro JF, del Rio I, Perez-Santana L. (1999) Preliminary studies of analgesic and anti-inflammatory properties of Opuntia dillenii aqueous extract. J. Ethnopharmacol. 67,213-218. https://doi.org/10.1016/S0378-8741(99)00027-6
  28. Meckes-Lozoya M, Ibanez-Camacho R. (1989) Hypoglucaemic activity of Opuntia streptacantha throughout its annual cycle. Am. J. Chin. Med. 17, 221-224. https://doi.org/10.1142/S0192415X89000310
  29. Moon C, Kim S, Ahn M, Lee S, Park S, Jeong K, Yoon DY, Choe YK, Shin T. (2000) Effects of Opuntia ficus indica extract on immune cell activation. Kor. J. Life Sci. 10,362-364.
  30. Mtambo MM, Mushi EJ, Kinabo LD, Maeda-Machang'u A, Mwamengele GL, Yongolo MG, Temu RP. (1999) Evaluation of the efficacy of the crude extracts of Capsicum frutescens, Citrus limon and Opuntia vulgaris against Newcastle disease in domestic fowl in Tanzania. J. Ethnopharmacol. 68, 55-61. https://doi.org/10.1016/S0378-8741(99)00032-X
  31. Park DS, Lee KH, Moon C, Son WG, Shin T. (2004) Supplementation with fermented Opuntia ficus-indica fruit powder increases growth rate of weaned pigs. Kor. J. Vet. Public Health 28, 23-28.
  32. Park EH, Chun MJ. (2001) Wound healing activity of Opuntia ficus-indica. Fitoterapia 72, 165-167. https://doi.org/10.1016/S0367-326X(00)00265-3
  33. Park EH, Kahng JH, Lee SH, Shin KH. (2001) An anti-inflammatory principle from cactus. Fitoterapia 72, 288-290. https://doi.org/10.1016/S0367-326X(00)00287-2
  34. Park EH, Kahng JH, Paek EA.(1998) Studies on the pharmacological action of cactus: identification of its anti-inflammatory effect. Arch. Pharm. Res. 21, 30-34. https://doi.org/10.1007/BF03216749
  35. Roman-Ramos R, Flores-Saenz JL, Partida-Hernandez G, Lara-Lemus A, Alarcon-Aguilar F. (1991) Experimental study of the hypoglycemic effect of some antidiabetic plants. Arch. Invest. Med. (Mex) 22, 87-93.
  36. Shin T, Kim S, Moon C, Wie M Hyun B. (1999) Opuntia ficus-indica ethanol extract ameliorates streptozotocin-induced hyperglycemia in rats. Kor. J. Gerontol. 9, 78-83.
  37. Stintzing FC, Schieber A, Carle R. (2002) Identification of betalains from yellow beet (Beta vulgaris L.) and cactus pear [Opuntia ficus-indica (L) Mil.] by high-performance liquid chromatography-electrospray ionization mass spectrometry. J. Agric. Food. Chem. 50, 2302-2307. https://doi.org/10.1021/jf011305f
  38. Takeda T, Hosokawa M, Takeshita S, Irine M Higuchi K, Matsushita T, Tomita Y, Yasuhira K, Hamamoto H, Shimizu K, Ishii M, Yamamuro T. (1981) A new murine model of accelerated senescence. Mech. Ageing Dev. 17, 183-194. https://doi.org/10.1016/0047-6374(81)90084-1
  39. Tesoriere L, Butera D, Pintaudi AM, Allegra M, Livrea MA. (2004) Supplementation with cactus pear (Opuntia ficus-indica) fruit decreases oxidative stress in healthy humans: a comparative study with vitamin G Am. J. Clin. Nutr. 80, 391-395.
  40. Trejo-Gonzalez A, Gabriel-Ortiz G, Puebla-Perez AM, Huizar-Contreras MD, Munguia-Mazariegos MR, Mejia-Arreguin S, Calva E. (1996) A purified extract from prickly pear cactus (Opuntia fuliginosa) controls experimentally induced diabetes in rats. J. Ethnopharmacol. 55, 27-33. https://doi.org/10.1016/S0378-8741(96)01467-5
  41. Wie MB. (2000) Protective effects of Opuntia ficus-indica and Saururus chinensis on free radical-induced neuronal injury in mouse cortical cell cultures. Yakhak Hoiji 44, 613.
  42. Wiese J, McPherson S, Odden MC, Shlipak MG. (2004) Effect of Opuntia ficus indica on symptoms of the alcohol hangover. Arch. Intern. Med. 164, 1334-1340. https://doi.org/10.1001/archinte.164.12.1334
  43. Wolfram R, Budinsky A, Efthimiou Y, Sto-matopoulos J, Oguogho A, Sinzinger H. (2003) Daily prickly pear consumption improves platelet function. Prostaglandins Leukot. Essent. Fatty Acids 69,61-66. https://doi.org/10.1016/S0952-3278(03)00057-7