생약학회지 (Korean Journal of Pharmacognosy)

한국생약학회 (The Korean Society of Pharmacognosy)
권호 표지

해조류인 뜸부기의 추출물이 지질대사에 미치는 영향

Effects of the Extracts from the Marine Algae Pelvetia siliquosa on Hyperlipidemia in Rats

  • 이연실 ((주) 월드씨그린 석원생명과학연구소) ;
  • 정상훈 (한국과학기술연구원) ;
  • 이상현 (서울대학교 약학대학) ;
  • 신국현 ((주) 월드씨그린 석원생명과학연구소)
  • Lee, Yeon-Sil (Seokwon Life Science Research Institute, World Sea Green Co. Ltd.) ;
  • Jung, Sang-Hoon (Natural Products Research Center, Korea institute of Science and Technology) ;
  • Lee, Sang-Hyun (College of Pharmacy, Seoul National University) ;
  • Shin, Kuk-Hyun (Seokwon Life Science Research Institute, World Sea Green Co. Ltd.)
  • 발행 : 2004.06.30
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초록

The effects of the MeOH and water extracts from the marine algae Pelvetia siliquosa were evaluated on hyperlipidemic rats induced by cholesterol rich diet or poloxamer-407. The MeOH and water extracts, when administered orally for 3 consecutive days in hyperlipidemic rats induced by poloxamer-407 (1 ml of 30%), were found to cause a significant decrease in plasma cholesterol and triglyceride concentrations. Both extracts also showed a significant inhibition of serum total cholesterol and triglyceride level in rats treated with cholesterol rich diet. HDL-cholesterol, however, was increased significantly.

키워드

참고문헌

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