Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Effects of the Extracts from the Marine Algae Pelvetia siliquosa on Hyperlipidemia in Rats

해조류인 뜸부기의 추출물이 지질대사에 미치는 영향

  • Lee, Yeon-Sil (Seokwon Life Science Research Institute, World Sea Green Co. Ltd.) ;
  • Jung, Sang-Hoon (Natural Products Research Center, Korea institute of Science and Technology) ;
  • Lee, Sang-Hyun (College of Pharmacy, Seoul National University) ;
  • Shin, Kuk-Hyun (Seokwon Life Science Research Institute, World Sea Green Co. Ltd.)
  • 이연실 ((주) 월드씨그린 석원생명과학연구소) ;
  • 정상훈 (한국과학기술연구원) ;
  • 이상현 (서울대학교 약학대학) ;
  • 신국현 ((주) 월드씨그린 석원생명과학연구소)
  • Published : 2004.06.30
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Abstract

The effects of the MeOH and water extracts from the marine algae Pelvetia siliquosa were evaluated on hyperlipidemic rats induced by cholesterol rich diet or poloxamer-407. The MeOH and water extracts, when administered orally for 3 consecutive days in hyperlipidemic rats induced by poloxamer-407 (1 ml of 30%), were found to cause a significant decrease in plasma cholesterol and triglyceride concentrations. Both extracts also showed a significant inhibition of serum total cholesterol and triglyceride level in rats treated with cholesterol rich diet. HDL-cholesterol, however, was increased significantly.

Keywords

References

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