The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)
- Volume 18 Issue 2
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- Pages.107-117
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- 2004
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- 1226-8038(pISSN)
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- 2287-9463(eISSN)
Effects of Arctii Fructus on the Atopic dermatitis
우방자(牛蒡子)가 아토피 피부염에 미치는 영향
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Lee, Jin-Yong
(Department of Pediatrics, College of Oriental Medicine, Kyunghee University) ;
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Kim, Deog-Gon
(Department of Pediatrics, College of Oriental Medicine, Kyunghee University) ;
- Han, Kyu-Chul (Department of Pediatrics, College of Oriental Medicine, Kyunghee University)
- Published : 2004.12.31
Abstract
Objective : Atopic dermatitis has a close relationship with degranulation of mast cell and separation of Histamine. As there's no experiment with herb, using Arctii Fructus, we investigated experimental influence of Arctii Fructus on degranulation of mast cell and separation of histamine in SD rat. Methods : The SD rats are classified into three groups. One group is normal one treated by normal saline before medical treatment. The other is control group prescribed to Compound 48/80 before normal saline treatment. And the third is experimental group prescribed to compound 48/80 after medical treatment of Arctii Fructus. Then, I investigated the experimental results by measuring the degree of degranulation and separation of histamine. The results of investigation on SD rat group showing the degree of inhibitory effect of degranulation of a mast cell are as follow, the normal group treated by normal saline reflecting the degree of degranulation is