The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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One Case of Drug-Induced Liver Injury Treated with Saenggangeonbi-tang

생간건비탕(生肝健脾湯)을 이용한 급성 약인성 간손상 치험 1례

  • Jeong, Tae-Young (Jeahan Oriental Medical Academy, Daegu Haany University) ;
  • Choi, Hong-Sik (Department of Internal Medicine, College of Oriental Medicine, Daegu Haany University)
  • 정태영 (대구한의대학교 제한동의학술원) ;
  • 최홍식 (대구한의대학교 간계내과학교실)
  • Published : 2004.12.30
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Abstract

Recently a case of liver injury from ingestion of Taeyeumjowi-tang containing Ma-huang(Ephedra sinica stapf) arose. The patient, a 30 year-old woman, was diagnosed with asthenia and anorexia after 6 weeks of ingesting Taeyeumjowi-tang containing Ma-huang(Ephedra sinica stapf) as a treatment for her obesity. Tests showed elevated levels of serum transaminase(ALT 903 IU/L, AST 716 IU/L), alkaline phosphatase (229 IU/L), total bilirubin (1.4 mg/dl). Other possible causes of liver injury were excluded by laboratory test and medical history, so the liver injury was taken to be drug-induced. Saenggangeonbi-tang was administered. After 2 weeks of treatment with this medication, the clinical symptoms and liver function improved. This case is reported with a call for further accumulation of objective data on drug-induced liver injury, and to bring more attention to the relative levels of safety and toxicity of herbal medicines.

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