The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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Study on Anti-tumor Activities of Both Hagocho and Byulap combined with Sambonggangyongbaneo-tang

삼봉강룡반어탕(三蓬薑龍半魚湯) 가(加) 하고초(夏枯草)와 加(가) 별갑(鱉甲)의 항암효과에 대한 비교연구

  • Park, Jung-Sup (Department of Internal Medicine, College of Oriental Medicine, Kyungwon University) ;
  • Jung, Seung-Min (Department of Internal Medicine, College of Oriental Medicine, Kyungwon University) ;
  • Yim, Young-Nam (Department of Internal Medicine, College of Oriental Medicine, Kyungwon University) ;
  • Ko, Ho-Yeun (Department of Internal Medicine, College of Oriental Medicine, Kyungwon University) ;
  • Han, Ji-Wan (Department of Internal Medicine, College of Oriental Medicine, Kyungwon University) ;
  • Kim, Dong-Woo (Department of Internal Medicine, College of Oriental Medicine, Kyungwon University)
  • 박정섭 (경원대학교 한의과대학 내과학교실) ;
  • 정승민 (경원대학교 한의과대학 내과학교실) ;
  • 임영남 (경원대학교 한의과대학 내과학교실) ;
  • 고호연 (경원대학교 한의과대학 내과학교실) ;
  • 한지완 (경원대학교 한의과대학 내과학교실) ;
  • 김동우 (경원대학교 한의과대학 내과학교실)
  • Published : 2004.12.30
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Abstract

In this piece of research, Prunellae spica is added to Sambonggangyongbaneotang for one group and Trionycis carapax is added to Sambonggangyongbaneotang for the other group. With these two different prescriptions, the degrees of tumor suppression are compared to develop a better prescription. SKH = Sambonggangyongbaneo-tang + Prunellae Spica SKB = Sambonggangyongbaneo-tang + Trionycis Carapax The results were as follows: 1. SKH and SKB demonstrated anti-tumor effects against tumor advancement of S-180 2. SKH and SKB showed on elevation of macrophage for tumor-bearing mice. 3. $100{\mu}g/ml,\;500{\mu}g/ml$ of SKH and $500{\mu}g/ml$ of SKB demonstrated a rise in alkaline phosphates of B-Lymphocyte in the spleen in tumor-bearing mice. Results support a role for both SKH and SKB for anti-tumor effects via endorsement of macrophage and encouragement of B-lymphocyte toward S-180.

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