대한한방내과학회지 (The Journal of Internal Korean Medicine)
- 제25권4호
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- Pages.274-288
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- 2004
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- 1226-9174(pISSN)
폐암세포주(肺癌細胞株) H460에 대(對)한 보중익기탕(補中益氣湯)의 세포고사효과(細胞枯死效果) 및 기전연구(機轉硏究)
Study on Apoptosis Effect and Mechanism by Bojungikki-tang on Human Cancer Cell Line H460
- 이승언 (원광대학교 한의과대학 폐계내과학교실) ;
- 홍재의 (원광대학교 한의과대학 폐계내과학교실) ;
- 이시형 (원광대학교 한의학 전문대학원) ;
- 신조영 (원광대학교 한의과대학 폐계내과학교실) ;
- 노승석 (원광대학교 한의과대학 폐계내과학교실)
- Lee, Seung-Eon (Department of Internal Medicine, College of Oriental Medicine, Wonkwang University) ;
- Hong, Jae-Eui (Department of Internal Medicine, College of Oriental Medicine, Wonkwang University) ;
- Lee, Si-Hyeong (Professional Graduate School of Oriental Medicine, Wonkwang University) ;
- Shin, Jo-Young (Department of Internal Medicine, College of Oriental Medicine, Wonkwang University) ;
- Ro, Seung-Seok (Department of Internal Medicine, College of Oriental Medicine, Wonkwang University)
- 발행 : 2004.12.30
초록
Objectives : This study was designed to evaluate the effect on cytotoxicity of Bojungikki-tang(BIT) in human lung cancer H460 cells. Methods : BIT-induced cell death was confirmed as apoptosis characterized by chromatin condensation and increase of the