Journal of Pharmacopuncture (대한약침학회지)

KOREAN PHARMACOPUNCTURE INSTITUTE (대한약침학회)
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The Review on the Prostate Disease-related Studies with Acupuncture Therapy in PubMed

PubMed 검색(檢索)을 이용한 전립선(前立腺) 질환(疾患)의 침치료(鍼治療)관련 연구(硏究)에 대한 고찰(考察)

  • Song, Ho-Sueb (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung Won University)
  • 송호섭 (경원대학교 한의과대학 침구학교실)
  • Published : 2004.06.25
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Abstract

Objective : This study was to review on the prostate disease-related studies with Acupuncture therapy in renowned medical internet site of PubMed, and to make master plan of the study, especially, on Bee Venom Acupuncture(BVA) of Prostate disease and then to devise the idealistic therapeutic ways of it. Method : We made the internet search with the key words of bee venom(bee venom therapy, apitoxin, apitherapy, bee sting, bee sting therapy), acupuncture, prostate, prostatitis, prostrate cancer in Pubmed, from June 1st to July 1st,2004. Results : 1.25 papers were found in 19 publised jounals. of which two named'Urology'and Prostate' had three papars, two called 'JUrology' and 'Cancer Immunol Immunother' had two papers, and the others had a paper respectively. 2. In the classification by papers' types, Review papers were 8 and Original were 17 where there were 5 clinical trials, 11 experimental studies and 1 epidemiologic paper. Of 5 clinical trials, 2 belonged to Randomized Control Study, and of 11 experimental studies, 4 belonged to in vitro and 7 belonged to in vivo with in viro studies, and 1 epidemeologic belonged to meta-analysis. 3. In the classification by prostate diseases, 4 were about prostatitis, 3 were about prostate related symptoms, 16 were about prostate cancer, and two were about the others. 4. In the classification by applied treatment methods, 5 were related with Acupuncture, 10 were related with BVA(Bee Venom, Bee), and 10 were related with the others. Of 5 related with Acupuncture, 3 used general acupuncture, 1 used electrical acupuncture, and 1 used general acupuncture and electrical acupuncture at the same time. 5. In 2 RCTs of Clinical trials, Control group was set up to the group using different compatible treatment method or using meridians not related with treating prostate disease. Single or double blind methods couldn't be found. 6. In the clinical trials, IPSS, NIH, CPSI or subjective global assessment were used as the Index of Evaluation. 7. The Leg Greater Yang Bladder Meridian(B), The Leg Lesser Um Kidney Meridian(K) and Conception Vessel Meridian(CV) were used as major meridians, and B10(Taejo, Dazhu), B23(Shinsu, Shenshu), B28(Panggwangsu, Pangguangshu), B35(Hoeyang, Huiyang), B39(Wiyang, Weiyang), B40(Wijung, Weizhong), B54(chilbyon, Zhibian), K1(Yongchon, Yongquan), K10(Umgok, Yingu), CV3(Chungguk, Zhongji), CV4(Kwanwon, Guanyuan),S6(Hyopko, Jiache) were used as acupoints. Electrical acupuncture(EA) was considered to be more important and CV3(Chungguk, Zhongji), CV4(Kwanwon, Guanyuan) were mainly selected as EA applied acupoints. 8. It is mostly said that Acupuncture appeared to be a safe, effective, and durable treatment alternative in improving symptoms of patients with prostate diseases, refractory to conventional medicine. A larger controlled study was required to confirm these encouraging initial results. Conclusion : Papers about BVA of Prostate cancer or Prostatitis were not found, and low permeability of Prostate is concerned, BVA with the anti-inflammatory and anti-cancer effect can be adopted as a new alternatives of Prostate disease treatment, so it is thought that Study of how to make access to prostate, animal experiment including in vivo and in vitro and more clinical trials with using acupoints on related meridian should be followed.

Keywords

References

  1. 김태우, 고형균, 박동석, 이재동. PubMed 검색을 이용한 관절염 관련 봉독 연구에 대한 고찰. 대한침구학회지. 2001;18(5):164–178.
  2. 윤형석, 이재동, 이윤호. 암관련 봉독 연구에 대한 고찰-PubMed를 이용한 Mediline검색. 대한침구학회지. 2000;17(4):69–78.
  3. 박경식, 함건주. 만성 세균성 전립선염 患者에서 전립선내 Fosfomycin Sodium의 직접 투여 效果. 인제의학. 1988;9(4):317–322.
  4. Moyad MA. Complementary/alternative therapies for reducing hot flashes in prostate cancer patients: reevaluating the existing indirect data from studies of breast cancer and postmenopausal women. Urology. 2002;59(4 Suppl 1):20–33.
  5. Chen R, Nickel JC. Acupuncture ameliorates symptoms in men with chronic prostatitis/chronic pelvic pain syndrome. Urology. 2003;61(6):1156–9. https://doi.org/10.1016/S0090-4295(03)00141-9
  6. Shoskes DA. Phytotherapy in chronic prostatitis. Urology. 2002;60(6 Suppl):35–7.
  7. Leuschner C, Enright FM, Gawronska-Kozak B, Hansel W. Human prostate cancer cells and xenografts are targeted and destroyed through luteinizing hormone releasing hormone receptors. Prostate 2003;56(4):239–49. https://doi.org/10.1002/pros.10259
  8. Leuschner C, Enright FM, Melrose PA, Hansel W. Targeted destruction of androgen-sensitive and -insensitive prostate cancer cells and xenografts through luteinizing hormone receptors. Prostate 2001;46(2):116–25. https://doi.org/10.1002/1097-0045(20010201)46:2<116::AID-PROS1015>3.0.CO;2-B
  9. Kim JH, Hong EK, Choi HS, Oh SJ, Kim KM, Uhm DY, Kim SJ. $K^{+}$ channel currents in rat ventral prostate epithelial cells. Prostate. 2002 May 15;51(3):201–10. https://doi.org/10.1002/pros.10090
  10. Johnstone PA, Bloom TL, Niemtzow RC, Crain D, Riffenburgh RH, Amling CL. A prospective, randomized pilot trial of acupuncture of the kidney-bladder distinct meridian for lower urinary tract symptoms. J Urol. 2003;169(3):1037–9.
  11. Hammar M, Frisk J, Grimas O, Hook M, Spetz AC. Wyon Y.Acupuncture treatment of vasomotor symptoms in men with prostatic carcinoma: a pilot study. J Urol. 1999;161(3):853–6.
  12. Russell PJ, Hewish D, Carter T, Sterling-Levis K, Ow K, Hattarki M, Doughty L, Guthrie R, Shapira D, Molloy PL, Werkmeister JA, Kortt AA. Cytotoxic properties of immunoconjugates containing melittin-like peptide 101 against prostate cancer: in vitro and in vivo studies. Cancer Immunol Immunother. 2004;53(5):411–21. https://doi.org/10.1007/s00262-003-0457-9
  13. Carter T, Sterling-Levis K, Ow K, Doughty L, Hattarki M, Shapira D, Hewish D, Kortt AA, Russell PJ. Biodistributions of intact monoclonal antibodies and fragments of BLCA-38, a new prostate cancer directed antibody. Cancer Immunol Immunother. 2004;53(6):533–42. https://doi.org/10.1007/s00262-003-0460-1
  14. Shoskes DA. Phytotherapy and other alternative forms of care for the patient with prostatitis. Curr Urol Rep. 2002;3(4):330–4. https://doi.org/10.1007/s11934-002-0059-7
  15. Shoskes DA, Manickam K. Herbal and complementary medicine in chronic prostatitis. World J Urol. 2003;21(2):109–13. https://doi.org/10.1007/s00345-003-0332-5
  16. Ricci L, Minardi D, Romoli M, Galosi AB, Muzzonigro G. Acupuncture reflexotherapy in the treatment of sensory urgency that persists after transurethral resection of the prostate: a preliminary report. Neurourol Urodyn 2004;23(1):58–62. https://doi.org/10.1002/nau.10105
  17. Oh WK, Small EJ. Complementary and alternative therapies in prostate cancer. Semin Oncol. 2002;29(6):575–84. https://doi.org/10.1053/sonc.2002.50007
  18. Weiger WA, Smith M, Boon H, Richardson MA, Kaptchuk TJ, Eisenberg DM. Advising patients who seek complementary and alternative medical therapies for cancer. Ann Intern Med. 2002 Dec;137(11):889–903. https://doi.org/10.7326/0003-4819-137-11-200212030-00010
  19. Smith MR. Complementary and alternative therapies for advanced prostate cancer. Hematol Oncol Clin North Am. 2001;15(3):559–71. https://doi.org/10.1016/S0889-8588(05)70232-X
  20. Moyad MA. Alternative therapies for advanced prostate cancer. What should I tell my patients? Urol Clin North Am. 1999 May;26(2):413–7. https://doi.org/10.1016/S0094-0143(05)70080-X
  21. Moyad MA, Hathaway S, Ni HS. Traditional Chinese medicine, acupuncture, and other alternative medicines for prostate cancer: an introduction and the need for more research. Semin Urol Oncol. 1999 May;17(2):103–10.
  22. Lokeshwar VB, Schroeder GL, Carey RI, Soloway MS, Iida N. Regulation of hyaluronidase activity by alternative mRNA splicing.J Biol Chem. 2002;277(37):33654–63.
  23. Cuesta-Rubio O, Frontana-Uribe BA, Ramirez-Apan T, Cardenas J. Polyisoprenylated benzophenones in cuban propolis; biological activity of nemorosone. Z Naturforsch [C]. 2002;57(3-4):372–8.
  24. Holle L, Song W, Holle E, Wei Y, Wagner T, Yu X. A matrix metalloproteinase 2 cleavable melittin/avidin conjugate specifically targets tumor cells in vitro and in vivo. Int J Oncol. 2003;22(1):93–8.
  25. Zaleska M, Bodek G, Jana B, Hansel W, Ziecik AJ. Targeted destruction of normal and cancer cells through lutropin/choriogonadotropin receptors using Hecate-betaCG conjugate. Exp Clin Endocrinol Diabetes. 2003;111(3):146–53. https://doi.org/10.1055/s-2003-39787
  26. Leuschner C, Enright FM, Gawronska B, Hansel W. Membrane disrupting lytic peptide conjugates destroy hormone dependent and independent breast cancer cells in vitro and in vivo. Breast Cancer Res Treat. 2003;78(1):17–27. https://doi.org/10.1023/A:1022169525521
  27. Gribenko AV, Guzman-Casado M, Lopez MM, Makhatadze GI. Conformational and thermodynamic properties of peptide binding to the human S100P protein. Protein Sci. 2002;11(6):1367–75. https://doi.org/10.1110/ps.0202202
  28. Ikeuchi T, Iguchi H. Electric acupuncture therapy for intractable cases of chronic prostatitis like syndrome. Hinyokika Kiyo. 1994;40(7):587–91.
  29. 전립선염의 신지견, 김광세. 계명대학교 논문집. 1984;3(1):8-17.
  30. 약침용 봉독성분 중 Apamin Melittin의 항암작용. 권도희, 이재동, 최도영. 대한침구학회지. 2001;18(1):129–145.
  31. 人體關節 滑膜細胞를 대상으로 한 봉약침(蜂藥鍼)液의 炎症 治療 및 機轉 硏究. 배철우, 송호섭. 대한침구학회지 2004;21(3):121–132.
  32. 봉약침액과 melittin이 RAW264.7세포의 NO, iNOS 및 Mark에 미치는 영향. 강준, 송호섭. 대한침구학회지. 2004;21(3):107–120.
  33. Effect of Acupuncture on Symptoms in a Patient with Interstitial Cystitis. 최유행, 이승덕, 김갑성. 대한침구학회지 2001;18(3):212–220.