Bulletin of the Korean Chemical Society

  • 제25권2호
  • /
  • Pages.195-197
  • /
  • 2004
  • /
  • 0253-2964(pISSN)
  • /
  • 1229-5949(eISSN)
대한화학회 (Korean Chemical Society)
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Biological Activities of Methyl-4-[[(2E)-3,7-dimethyl-oxy]-3-hydroxybenzoate

  • Baek, Seung-Hwa (Department of Herbal Resources, Professional Graduate School of Oriental Medicine and Institute of Basic Natural Sciences, Wonkwang University) ;
  • Oh, Hyun-Ju (Department of Herbal Resources, Professional Graduate School of Oriental Medicine and Institute of Basic Natural Sciences, Wonkwang University) ;
  • Lim, Jin-A (Department of Herbal Resources, Professional Graduate School of Oriental Medicine and Institute of Basic Natural Sciences, Wonkwang University) ;
  • Chun, Hyun-Ja (Division of natural Sciences, Wonkwang University) ;
  • Lee, Hyun-Ok (Department of Dental Hygiene, Wonkwang Health Science College) ;
  • Ahn, Jong-Woong (Division of Ocean Science, College of Ocean Science and Technology, Korea Maritime University) ;
  • Perry, Nigel B. (Plant Extracts Research Unit, New Zealand Institute for Crop & Food Research Ltd, Department of Chemistry, Otago University) ;
  • Kim, Hyung-Min (Department of Pharmacology, School of Oriental Medicine, Kyung Hee University)
  • 발행 : 2004.02.20
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초록

Methyl-4-[[(2E)-3,7-dimethyl-2,6-octadienyl]oxy]-3-hydroxybenzoate (5) has been identified from the New Zealand liverwort Trichocolea hatcheri (T. hatcheri) on the basis of spectroscopic evidence. This compound was tested for its growth inhibitory effects against tumor cell lines, using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay. It showed growth inhibition activity against Staphylococcus epidermidis (MIC, 1,000 ${\mu}$g/mL). These results suggest that compound 5 possesses antitumoral , antimicrobial and antioxidative activities.

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참고문헌

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피인용 문헌

  1. Biological Activities of Methyl-4-[[(2E)-3,7-dimethyl-2,6-octadienyl]oxy]-3-hydroxybenzoate. vol.35, pp.33, 2004, https://doi.org/10.1002/chin.200433233
  2. Matrix Metalloproteinase-1 Inhibitor from the Aerial Parts of Viola ibukiana MAKINO vol.26, pp.3, 2004, https://doi.org/10.5012/bkcs.2005.26.3.451
  3. Biological Activity of Bioactive Components from Acer ginnala Max. vol.26, pp.9, 2004, https://doi.org/10.5012/bkcs.2005.26.9.1450
  4. Phytochemical and biological studies of bryophytes vol.91, pp.None, 2004, https://doi.org/10.1016/j.phytochem.2012.04.012
  5. Pungent and Bitter, Cytotoxic and Antiviral Terpenoids from Some Bryophytes and Inedible Fungi vol.9, pp.3, 2004, https://doi.org/10.1177/1934578x1400900331
  6. Design, Synthesis and Antiproliferative Activity Evaluation of New 5-Azaisoindigo Derivatives vol.89, pp.8, 2004, https://doi.org/10.3987/com-14-13036
  7. Phytochemistry of the Genus Trichocolea vol.13, pp.9, 2018, https://doi.org/10.1177/1934578x1801300924