대한한방내과학회지 (The Journal of Internal Korean Medicine)
- 제25권1호
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- Pages.106-118
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- 2004
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- 1226-9174(pISSN)
갈화(葛花)의 항돌연변이(抗突然變異) 활성(活性)에 관한 연구(硏究)
A Study on Antimutagenic acitivities of from Puerariae Flos Extracts
- 정영재 (동국대학교 한의과대학 내과학교실) ;
- 김미랑 (동국대학교 한의과대학 내과학교실) ;
- 정지천 (동국대학교 한의과대학 내과학교실) ;
- 서운교 (동국대학교 한의과대학 내과학교실)
- Jeong Young-Jae (Department of Internal Medicine, College of Oriental Medicine, Dongguk University) ;
- Kim Mi-Rang (Department of Internal Medicine, College of Oriental Medicine, Dongguk University) ;
- Jeong Ji-Cheon (Department of Internal Medicine, College of Oriental Medicine, Dongguk University) ;
- Seo Woon-Gyo (Department of Internal Medicine, College of Oriental Medicine, Dongguk University)
- 발행 : 2004.12.01
초록
Antigenotoxicity test (SOS chromotest), antimutagenecity test (Ames test), and antioxidant test (NBT method and xanthine-xanthine oxidase method) were carried out using water-soluble and methanolic extracts from Puerariae Flos. Against the mutagens MNNG and NQO, antigenotoxic activity of methanolic extracts were much more effective than that of water-soluble ones. When the methanolic extract was added to the certain concentration
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