歸脾湯 및 歸脾湯加味方의 止血效果에 관한 實驗的 硏究

A Study on the Homostatic Effects of Guipitang and Guipitangjiaweifang Extracts in Experimental Animals

This Experiment was conducted to investigate the hemostatic effects of Guipitang and Guipitangjiaweifang. For this purpose, the effects of the crude extracts on the platelet count. prothrombin time, fibrinogen level and partial prothromboplastin time were estimated. The rats were divided into normal group, control group and experimental group. Control group was administrated normal saline and experimental group was divided into Sample 1 (Guipitang) and Sample 2 (Guipitangjiaweifang). The results obtained were as follows : 1. The platelet count was significantly increased in both of two samples as compared with the control group. 2. The prothrombin time was significantly shortened in case of Sample 2. however there were no significant changes in case of Sample 1 as compared with the control group. 3. The fibrinogen level was significantly increased in case of Sample 1. however there were no meaningful changes in case of Sample 2 as compared with the control group. 4. The partial prothromboplastin time was significantly shortened in both of two samples as compared with the control group. According to above results. it is supposed that Guipitang and Guipitangjiaweifang have the hemostatic effects in experimental animals.