기흉에 의해 발견된 이상성 폐 모세포종

Biphasic Pulmonary Blastoma detected by Pneumothorax

본례에서는 자연적으로 발생한 기흉으로 발견된 이상성 폐 모세포종을 수술과 cisplatin에 의한 화학요법을 시행하여 성공적으로 시험하였기에 문헌 고찰과 함께 보고하는 바이다.

Pulmonary blastoma is a rare primary lung neoplasm composed of a mixture of immature mesenchyme and epithelium that morphologically mimics embryonal pulmonary structure. Microscopically, tumors could be divided into two classes; those composed solely of malignant glands of epithelial components (well-differentiated fetal adenocarcinoma) and those with biphasic appearance. A 51-year-old man was admitted with left sided pneumothorax. After closed thoracostomy, chest X-ray showed a circular mass in the left lower zone. The tumor was diagnosed as adenocarcinoma as a result of percutaneous needle aspiration biopsy, and left lower lobectomy was performed. The patient was diagnosed as having biphasic pulmonary blastoma on postoperative histological assessment. This case is the first reported patient with biphasic pulmonary blastoma detected by pneumothorax.