Clinical and Experimental Pediatrics
- Volume 46 Issue 8
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- Pages.817-820
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- 2003
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- 2713-4148(eISSN)
Alteration of Biochemical Profiles after High-Dose Intravenous Immunoglobulin Administration in Kawasaki Disease
가와사끼병에서 고용량 정맥용 면역글로불린 투여 후 생화학 지표들의 변화
- Lee, Ji-Won (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
- Lee, Kyung-Yil (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
- Received : 2003.01.09
- Accepted : 2003.04.30
- Published : 2003.08.15
Abstract
Purpose : Intravenous immunoglobulin(IVIG) has been used as an immunomodulatory treatment for several immune-mediated diseases. The early effect of high-dose IVIG on biochemical profiles including lipids and proteins was evaluated in patients with Kawasaki disease(KD). Methods : Twelve children with KD(nine boys) were treated with IVIG of 2 g/kg over 12 hours. Serial sera were collected from the patients four times : before IVIG treatment and two hours, 24 hours and seven days after IVIG treatment. The samples were frozen at
목 적 : IVIG은 다양한 면역 질환에서 면역 조절제로 사용되고 있다. 가와사끼병에서 고용량의 IVIG 투여가 단백과 지질을 포함한 다양한 생화학적 지표에 미치는 영향을 알아보고자 하였다. 방 법 : IVIG(2 g/kg)을 투여받은 12 명의 가와사끼병 환아에 대해 IVIG 투여 전, 2시간, 24시간 및 7일 후에 혈청을 분리하고