IMMUNE NETWORK
- 제3권2호
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- Pages.126-135
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- 2003
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- 1598-2629(pISSN)
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- 2092-6685(eISSN)
Phage Display 방법을 이용한 B형 간염 바이러스의 Terminal Protein 특이 scFv 항체 생산
Terminal Protein-specific scFv Production by Phage Display
- 이명신 (아주대학교 의과대학 미생물학교실) ;
- 권명희 (아주대학교 의과대학 미생물학교실) ;
- 박선 (아주대학교 의과대학 미생물학교실) ;
- 신호준 (아주대학교 의과대학 미생물학교실) ;
- 김형일 (아주대학교 의과대학 미생물학교실)
- Lee, Myung-Shin (Department of Microbiology, Ajou University School of Medicine) ;
- Kwon, Myung-Hee (Department of Microbiology, Ajou University School of Medicine) ;
- Park, Sun (Department of Microbiology, Ajou University School of Medicine) ;
- Shin, Ho-Joon (Department of Microbiology, Ajou University School of Medicine) ;
- Kim, Hyung-Il (Department of Microbiology, Ajou University School of Medicine)
- 발행 : 2003.06.30
초록
Background: One of the important factors in the prognosis of chronic hepatitis B patient is the degree of replication of hepatitis B virus (HBV). It has been known that HBV DNA polymerase plays the essential role in the replication of HBV. HBV DNA polymerase is composed of four domains, TP (Terminal protein), spacer, RT (Reverse transcriptase) and RNaseH. Among these domains, tyrosine, the