IMMUNE NETWORK
- Volume 3 Issue 2
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- Pages.103-109
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- 2003
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- 1598-2629(pISSN)
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- 2092-6685(eISSN)
Distribution of HLA-DQA1*01, *03, *05 and DQB1*02 Subtypes and the Associated Haplotypes in the Korean Population
- Pyo, Chul-Woo (Catholic Hemopoietic Stem Cell Bank, College of Medicine, The Catholic University of Korea) ;
- Chung, Seo-Young (Catholic Hemopoietic Stem Cell Bank, College of Medicine, The Catholic University of Korea) ;
- Hur, Seong-Suk (Catholic Hemopoietic Stem Cell Bank, College of Medicine, The Catholic University of Korea) ;
- Kim, Hyoung-Jae (Catholic Hemopoietic Stem Cell Bank, College of Medicine, The Catholic University of Korea) ;
- Choi, Jee-Yeoun (Catholic Hemopoietic Stem Cell Bank, College of Medicine, The Catholic University of Korea) ;
- Kim, Yang-Kyum (Catholic Hemopoietic Stem Cell Bank, College of Medicine, The Catholic University of Korea) ;
- Yoo, Ha-Jung (Catholic Hemopoietic Stem Cell Bank, College of Medicine, The Catholic University of Korea) ;
- Choi, Hee-Baeg (Catholic Hemopoietic Stem Cell Bank, College of Medicine, The Catholic University of Korea) ;
- Kim, Tai-Gyu (Catholic Hemopoietic Stem Cell Bank, College of Medicine, The Catholic University of Korea)
- Published : 2003.06.30
Abstract
Background: As all HLA class II genes, the DQ genes show their polymorphic variation mainly in the second exon, which encodes the first extracellular domain of the molecule. PCR-SSOP (Polymerase chain reaction-Sequence specific oligonucleotide probe) techniques were frequently used for HLA-DQA1 and DQB1 typing but certain alleles,