A fMRI study on the cerebral activity induced by Electro-acupuncture on Taichong(Liv3)

태충(太衝)(Liv3)의 전침자극(電鍼刺戟)이 fMRI상 뇌활성(腦活性) 변화(變化)에 미치는 영향(影響)

  • Ha, Chi-hong (Deptartmet of Acpuncture & Moxibustion Meridian College of Oriental Medicine, Dae-Jeon University) ;
  • Lee, Hyun (Deptartmet of Acpuncture & Moxibustion Meridian College of Oriental Medicine, Dae-Jeon University) ;
  • Lim, Yun-kyoung (Deptartmet of Acpuncture & Moxibustion Meridian College of Oriental Medicine, Dae-Jeon University) ;
  • Hong, Kwon-eui (Deptartmet of Acpuncture & Moxibustion Meridian College of Oriental Medicine, Dae-Jeon University) ;
  • Lee, Byung-ryul (Deptartmet of Acpuncture & Moxibustion Meridian College of Oriental Medicine, Dae-Jeon University) ;
  • Kim, Yeon-jin (Deptartmet of Diagnostic Radiology Hae-Hwa Hospital, Dae-Jeon University)
  • 하치홍 (대전대학교 한의과대학 침구경혈학교실) ;
  • 이현 (대전대학교 한의과대학 침구경혈학교실) ;
  • 임윤경 (대전대학교 한의과대학 침구경혈학교실) ;
  • 홍권의 (대전대학교 한의과대학 침구경혈학교실) ;
  • 이병렬 (대전대학교 한의과대학 침구경혈학교실) ;
  • 김연진 (대전대학교 부속 혜화병원 진단방사선과학교실)
  • Received : 2003.07.04
  • Accepted : 2003.07.20
  • Published : 2003.10.20

Abstract

Objective: Recently, many studies have showed the evidences of the effect of the acupuncture treatment through scientific methods. One of these methods is functional MRI. We performed electro-acupuncture on Liv3 and observed the change of brain activation using fMRI. Methods: To see the effect of electro-acupuncture stimulation on Liv3. the experiment was carried out on 12 healthy volunteers. using the gradient echo sequence with the 3.0T whole-body MRI system(ISOL). After the needle insertion on right Liv3. 2 Hz of electric stimulation was given for 30 seconds. repeated five times. with 30 seconds' intervals. The Image analysis including motion correction, talairach transformation. and smoothing was done with SPM99. Results : 1. Group averaged brain activation induced by bilateral electro-acupuncture stimulation on Liv3 activates Brodman Area 6, 13, 18, 19, 22, 31, 39, 44, 2. Group averaged brain deactivation induced by bilateral Electro-acupuncture stimulation on Liv3 activates Brodman Area 4, 6, 9, 19, 36, 37, 39. 3. Group averaged brain activation induced by unilateral(right side) electro-acupuncture stimulation on Liv3 activates Brodman Area 2, 3, 6, 9, 10, 22, 40, 42, 43. 4. Group averaged brain deactivation induced by unilateral(right side) electro-acupuncture stimulation on Liv3 activates Brodman Area 6, 18, 19, 28, 30, 31, 35, 37. 5. Brain region activated by motor stimulation activates Brodman Area 4, 6, 13, 19, 42.

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