Journal of Periodontal and Implant Science

Korean Academy of Periodontology (대한치주과학회)
권호 표지

Histologic evaluation of $Regenafil^{TM}$ on defects of extraction socket

발치와의 결손부위에 $Regenafil^{TM}$의 임상적 적용에 관한 조직학적 연구

  • Kye, Seung-Beom (Dept. of Periodontics, Samsung Medical Center, Sungkunkwan University School of Medicine) ;
  • Yang, Seung-Min (Dept. of Periodontics, Samsung Medical Center, Sungkunkwan University School of Medicine) ;
  • Seol, Yang-Jo (Dept. of Periodontics, Samsung Medical Center, Sungkunkwan University School of Medicine) ;
  • Lee, Young-Kyoo (Dept. of Periodontics, Samsung Medical Center, Sungkunkwan University School of Medicine)
  • 계승범 (성균관대학교 의과대학 삼성서울병원 치과진료부 치주과) ;
  • 양승민 (성균관대학교 의과대학 삼성서울병원 치과진료부 치주과) ;
  • 설양조 (성균관대학교 의과대학 삼성서울병원 치과진료부 치주과) ;
  • 이영규 (성균관대학교 의과대학 삼성서울병원 치과진료부 치주과)
  • Published : 2003.09.30
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Abstract

The purpose of this study is to evaluate histologic result of bone substituting material on defects followed tooth extraction. We compare the histologic findings control, DFDBA, Bio-Oss(R), and $Regenafil^{TM}$, Briefly, mandibular premolar teeth were extracted available for bone filling. All alveolar sites were checked after extraction and thoroughly debrided with a dental curet to remove the periodontal ligament. Extraction sites were prepared dehiscence on buccal side 7mm height from alveolar crest. The graft materials were filled into the extraction socket and dehiscenc defects. The animals were sacrificed 12 weeks after implantation. Both treated and control mandibular sites were histologically evaluated with light microscopy. Histologic observation at 12 weeks revealed that control and experimental sites were healed uneventfully and directly apposed to new bone without any adverse tissue reaction. DFDBA and Bio-Ossn(R)sites maintain width of alveolar crest but were not fully resorbed. $Regenafil^{TM}$ sites also maintain width and particles were resorbed more than other graft materials. From this results, it was suggested that $Regenafil^{TM}$ is promising boen substituting materials maintaining the width of alveolar crest and height follewed tooth extraction.

Keywords

References

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