The Korean Journal of Cytopathology (대한세포병리학회지)

The Korean Society for Cytopathology (대한세포병리학회)
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Urine Cytology of Prostatic Adenocarcinoma -A Case Report-

전립샘 샘암종의 뇨 세포학적 소견 -1예 보고-

  • Lee, Won-Ae (Department of Pathology, Collage of Medicine, Dankook University) ;
  • Kwon, Mi-Seon (Department of Pathology, Collage of Medicine, Dankook University) ;
  • Ko, Jai-Hyang (Department of Pathology, Collage of Medicine, Dankook University) ;
  • Myong, Na-Hye (Department of Pathology, Collage of Medicine, Dankook University)
  • 이원애 (단국대학교 의과대학 병리학교실) ;
  • 권미선 (단국대학교 의과대학 병리학교실) ;
  • 고재향 (단국대학교 의과대학 병리학교실) ;
  • 명나혜 (단국대학교 의과대학 병리학교실)
  • Published : 2003.11.30
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Abstract

Prostatic adenocarcinoma cells can be detected in urine cytology specimens when the tumor extends to the bladder mucosa. We report a case of prostatic adenocarcinoma diagnosed by urine cytology. A 70-year-old man presented with urinary frequency and low back pain On rectal examination, a nodular mass was palpated in the left side of prostate. Bone scan revealed multifocal hot lesions suggesting metastasis. Urine cytology revealed hypocellular smear on clean or bloody background. Tumor cells were mainly arranged in syncytial or papillary clusters which occasionally contained fool of luminal formation The cytoplasm of tumor cells was finely granular. The nuclei of tumor cells revealed evenly distributed fine chromatin and large prominent nucleoli without nuclear pleomorphism. In needle biopsy specimen of prostate, tumor cells were detected in entire prostatic tissue with extension to pericapsular soft tissue. The tumor cells infiltrated individually or in a cord-like fashion with fool of cribriform pattern. Inconspicuous nuclear pleomorphism and prominent nucleoli were also noted.

Keywords

References

  1. Vanna VA, Fekete PS, Franks MJ, Walther MM. Cytological features of prostate adenocarcinoma in urine: a clinico-pathologic and immuno-histochemical study. Diagn Cytopathol 1988;4:300-5 https://doi.org/10.1002/dc.2840040406
  2. Bardales RH, Pitman MB, Stanley MW, Korourian S, Suhrland MJ. Urine cytology of primary and secondary urinary bladder adenocarcinoma. Cancer 1998;84:335-43 https://doi.org/10.1002/(SICI)1097-0142(19981225)84:6<335::AID-CNCR4>3.0.CO;2-W
  3. Rupp M, O'Hara B, McCullogh L, Socrates J. Prostatic carcinoma in urine specimens: cytologic, histologic and immunohistochemical features. Acta Cytol 1990;34:744-5
  4. Krishnan B, Truong LD. Prostatic adenocarcinoma diagnosed by urinary cytology. Am J Clin Pathol 2000;113:29-34 https://doi.org/10.1309/4T6H-549R-CAPJ-FEY0
  5. Rupp M, O'Hara B, McCullough L, Saxena S, Olchiewski J. Prostatic carcinoma cells in urine specimens. Cytopathology 1994;5:164-70 https://doi.org/10.1111/j.1365-2303.1994.tb00412.x
  6. Garret M, Jassie M. Cytologic examination of post-prostatic massage specimens as an aid in diagnosis of carcinoma of the prostate. Acta Cytol 1976;20:126-31
  7. Goessl C, Muller M, Heicappell R, et al. DNA-basesd detection of prostate cancer in urine after prostatic massage. Urology 2001;58:335-8 https://doi.org/10.1016/S0090-4295(01)01268-7
  8. Ooms EC, Kurver PJ, Boon ME. Morphometrical analysis of urothelial cells in voided urine of patients with low grade and high grade bladder tumors. J Clin Pathol 1982;35:1063-5 https://doi.org/10.1136/jcp.35.10.1063
  9. Piscoli F, Detassis C, Polla E, et al. Cytologic presentation of renal adenocarcinoma in urinary sediment. Acta Cytol 1983;27:383-90
  10. Ramzy I, Larson V. Prostatic duct carcinoma: exfoliative cytology. Acta Cytol 1977;21:417-20
  11. Vandersteen DP, Wiemerslage SJ, Cohen MB. Prostatic duct adenocarcinoma: a cytologic and histologic case report with review of the literature. Diagn Cytopathol 1997;17:480-3 https://doi.org/10.1002/(SICI)1097-0339(199712)17:6<480::AID-DC20>3.0.CO;2-H