Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Screening for Biological Activity of Crude Extract and Bioactive Fractions from Brachyglottis monroi

  • Baek Seung Hwa (Department of Herbal Resources, Professional, Graduate School of Oriental Medicine and Institute of Basic Sciences, Wonkwang University) ;
  • Lim Jin A (Department of Herbal Resources, Professional, Graduate School of Oriental Medicine and Institute of Basic Sciences, Wonkwang University) ;
  • Kwag Jung Sook (Department of Dental Hygiene, Mokpo Science College) ;
  • Lee Hyun Ok (Department of Dental Hygiene, Wonkwang Health Science College) ;
  • Chun Hyun Ja (Department of Third Medicine, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Lee Jeong Ho (Division of Natural Sciences, Wonkwmng University) ;
  • Perry Nigel B. (Plant Extracts Research Unit, New Zealand Institute for Crop & Food Research Ltd, Department of Chemistry, Otago University)
  • Published : 2003.06.01
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Abstract

The effects of crude extract and bioactive fractions from Brachyglottis monroi on biological activity were investigated. The crude ethanol extract inhibited the growth of the Gram positive bacterium Bacillus subtilis (ATCC Strain number 19659, 1 mm zone at 150 μg/disk) and the dermatophyte Trichophyton mentagrophytes (ATCC 28185, 2 mm zone at 150 μg/disk), and toxic to P388 tumor cells (IC50 23.96 μg/ml at 75 μg/disk). Cytotoxic activity was strongly showed by Fr. 6 (P388 IC50 19.67 μg/ml at 75 μg/disk).

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References

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