Clinic Study of Gami-Yunbueum Efficacy on the Psoriasis

건선에 대한 가미윤부음의 임상연구

  • Kim Byoung Soo (Department of Physiology, College of Oriental Medicine, Daejeon University) ;
  • Lee Sangkeun (Institute of Traditional Medicine & Bioscience, Daejeon University) ;
  • Lee Jeung Haem (Department of dermatology, College of Medicine, Chungnam National University) ;
  • Lim Jong Soon (Institute of Traditional Medicine & Bioscience, Daejeon University) ;
  • Kang Jung-Soo (Department of Physiology, College of Oriental Medicine, Daejeon University)
  • 김병수 (대전대학교 한의과대학 생리학교실) ;
  • 이상근 (대전대학교 동서생명과학연구원) ;
  • 이증훈 (충남대학교 의과대학 피부과) ;
  • 임종순 (대전대학교 동서생명과학연구원) ;
  • 강정수 (대전대학교 한의과대학 생리학교실)
  • Published : 2003.12.01

Abstract

Psoriasis is a common inflammatory disease of the skin marked by excessive scaling associated with inflammation, affecting 1-2% of the population. Although their etiologies remain unknown, the finding of CD4+ and CD8+ lymphocytes at sites of psoriasis has led many reports to hypothesize that psoriasis is a T lymphocyte-mediated disease directed against unknown autoantigens. The oriental medicine understands the cause of psoriasis as low humidity of skin tissues and functional deteriorations of the liver and lung. Gami-Yunbueum (GY) is a mixture of two previous prescription, which were used to the protection of liver and lung. We had prescribed the GY to the three psoriasis patients for 11 weeks and examined the effectiveness of the GY by PASI (Psoriasis Area and Severity Index) score. In our experiment, GY improved the symptoms of psoriasis in all cases. These results indicated that GY can apply to the treatment of psoriasis. Furthermore, the process for treatment of psoriasis is possible to provide humidity to skin and control the functions of liver and lung.

Keywords

References

  1. 건선(건선 아트라스) 윤재일
  2. 윤재일박사의 건선클리닉 윤재일
  3. 피부과학(개정4판) 대한피부과학회 교과서 편찬위원회
  4. 한의학대사전 한의학대사전편찬위원회
  5. 諸病源候論(中國醫學大系2券) 巢元方
  6. 中醫外科學 上海中醫學院(編)
  7. 醫宗金鑑(中國醫學大系50券) 吳謙
  8. 동의생리병리학회지 v.16 no.4 燥濕觀點에서 본 乾癬 연구 김병수;국순호;강정수
  9. 한글판 중의 乾癬의 주요 병기가 陰虛瘀血임을 논증 王暉 施天寧
  10. 방약합편해설 신재용
  11. 赤水玄珠(中國醫學大系34券) 孫一奎
  12. 醫門法律(中國醫學大系51券) 喩昌
  13. 변증론치 방약합편 黃度淵
  14. 本草學 전국한의과대학 본초학교실
  15. 原本醫方集解 汪昻
  16. 동의임상방제학 윤길영
  17. Science v.230 Psoriatic fibroblasts induce hyperproliferation of normal keratinocytes in a skin equivalent model in vitro Saiag, P.;Coulomb, B.;Lebreton, C.;Bell, E.;Dubertret, L.
  18. Trends Immunol. v.23 no.1 Novel immunotherapies for psoriasis Asadullah, K.;Volk, H.D.;Sterry, W.
  19. J Clin Invest. v.104 no.9 Skin innate immune system in psoriasis: friend or foe? Nickoloff, B.J.
  20. Immunol Today. v.20 no.1 The pathogenesis of psoriasis: immunological facts and speculations Bos, J.D.;De Rie, M.A.
  21. Trends Cell Biol. v.11 no.4 Paracrine regulation of keratinocyte proliferation and differentiation Werner, S.;Smola, H.