Clinical and Experimental Reproductive Medicine

The Korean Society for Reproductive Medicine (대한생식의학회)
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Multiple Attempts at Embryo Transfer do not Adversely Affect In-vitro Fertilization Pregnancy Rates: Related Mucus Contamination

반복 배아 이식이 임신율에 미치는 영향: 이식관의 점액 유무

  • Jung, Byeong-Jun (Department of Obstetrics and Gynecology, Seoul Women's Hospital) ;
  • Kim, Jong-Sik (Infertility Center, Seoul Women's Hospital) ;
  • Kwon, Cheo-Jin (Infertility Center, Seoul Women's Hospital) ;
  • Ryu, Mi-Jin (Infertility Center, Seoul Women's Hospital) ;
  • Kim, Myung-Sin (Infertility Center, Seoul Women's Hospital) ;
  • Kang, Eun-Hee (Department of Obstetrics and Gynecology, Seoul Women's Hospital) ;
  • Sim, Jong-Ok (Department of Obstetrics and Gynecology, Seoul Women's Hospital) ;
  • Song, Hyun-Jin (Department of Obstetrics and Gynecology, Seoul Women's Hospital) ;
  • Oh, Ik-Hwan (Department of Obstetrics and Gynecology, Seoul Women's Hospital)
  • 정병준 (인천 서울여성병원 산부인과) ;
  • 김종식 (인천 서울여성병원 불임센터) ;
  • 권처진 (인천 서울여성병원 불임센터) ;
  • 유미진 (인천 서울여성병원 불임센터) ;
  • 김명신 (인천 서울여성병원 불임센터) ;
  • 강은희 (인천 서울여성병원 산부인과) ;
  • 심종옥 (인천 서울여성병원 산부인과) ;
  • 송현진 (인천 서울여성병원 산부인과) ;
  • 오익환 (인천 서울여성병원 산부인과)
  • Published : 2003.03.30
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Abstract

Objective : We investigate the effects of multiple attempts of embryo transfer because of retained embryos in the catheter and of contaminated mucus on the transferred catheter. Materials and Methods: We respectively analysed data between November 1998 and August 2002 from 305 patients of 369 cycles who underwent IVF-ET. Of these patients, 47 patients of 50 cycles (Group 2) were required multiple trial of embryo transfer. They were compared with an age-matched control groups (Group 1) with female factor infertility. Pearson's $?^2$ and Fisher's tests were used to compare proportions between discrete variables. Noncategorical data were compared using t-test. Statistical significance was set at p<0.05. Results: Embryos were significantly more likely to be retained when catheter was contaminated with mucus (Group 1: 22.4%; Group 2: 44.0%). The clinical pregnancy rates, however, for the contaminated mucus or not, were 46.8%, 43.5% respectively. There was no significant difference clinical pregnancy rate between those who had all their embryos transferred at the first attempt (45.4%) and those who required more than one attempt (48.0%). Conclusions: Contaminated mucus in the catheter is associated with failed embryo transferred at the first attempt. Embryo transfers, however, that are repeated attempts do not adversely affect pregnancy rates following IVF-ET.

Keywords

References

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