Environmental Mutagens and Carcinogens (한국환경성돌연변이발암원학회지)
- Volume 23 Issue 3
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- Pages.85-93
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- 2003
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- 1225-6307(pISSN)
Manganese Distribution in Brains of Sprague Dawley Rats after 60 Days of Stainless Steel Welding-Fume Exposure
- Yu, Il-Je (Center for Occupational Toxicology, Occupational Safety and Health Research Institute, Korea Occupational Safety Health Agency, College of Pharmacy, Sung Kyun Kwan University) ;
- Park, Jung-Duck (College of Medicine, Chung-Ang University) ;
- Park, Eon-Sub (College of Medicine, Chung-Ang University) ;
- Song, Kyung-Seuk (Center for Occupational Toxicology, Occupational Safety and Health Research Institute, Korea Occupational Safety Health Agency, College of Pharmacy, Sung Kyun Kwan University) ;
- Han, Kuy-Tae (Korea Dusturbo Incorporation) ;
- Han, Jeong-Hee (Center for Occupational Toxicology, Occupational Safety and Health Research Institute, Korea Occupational Safety Health Agency) ;
- Chung, Yong-Hyun (Center for Occupational Toxicology, Occupational Safety and Health Research Institute, Korea Occupational Safety Health Agency) ;
- Choi, Byung-Sun (College of Medicine, Chung-Ang University) ;
- Chung, Kyu-Hyuck (College of Pharmacy, Sung Kyun Kwan University) ;
- Cho, Myung-Haeng (College of Veterinary Medicine, seoul National University)
- Published : 2003.09.01
Abstract
Welders working in a confined space, like in the shipbuilding industry, are at risk of being exposed to high concentrations of welding fumes and developing pneumoconiosis or other welding-fume exposure related diseases. Among such diseases, manganism resulting from welding-fume exposure remains a controversial issue, as the movement of manganese into specific brain regions has not been clearly established. Accordingly, to investigate the distribution of manganese in the brain after welding-fume exposure, male Sprague Dawley rats were exposed to welding fumes generated from manual metal arc stainless steel (MMA-SS) at concentrations of
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