Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Oral Malignant Melanoma in a Labrador Retriever

리트리버 개의 구강유래 악성 흑색종 발생 예

  • Ji-Yun, Lee (Department of Veterinary Internal Medicine and Veterinary Surgery, College of Veterinary Medicine, Konkuk University) ;
  • Sang-Yeon, Oh (College of Veterinary Medicine, Seoul National University) ;
  • Dae-Yong, Kim (College of Veterinary Medicine, Seoul National University) ;
  • Chul, Park (Department of Veterinary Internal Medicine and Veterinary Surgery, College of Veterinary Medicine, Konkuk University) ;
  • Hun-Young, Yoon (Department of Veterinary Internal Medicine and Veterinary Surgery, College of Veterinary Medicine, Konkuk University) ;
  • Soon-Wuk, Jeong (Department of Veterinary Internal Medicine and Veterinary Surgery, College of Veterinary Medicine, Konkuk University) ;
  • Hee-Myung, Park (Department of Veterinary Internal Medicine and Veterinary Surgery, College of Veterinary Medicine, Konkuk University)
  • Published : 2003.12.01
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Abstract

A 12-year-old, intact male Labrador Retriever was admitted to the Veterinary Teaching Hospital of Konkuk University for the evaluation of bleeding mass in the oral cavity. The mass was first noted 2 years ago and has been growing up to a size of $5{\times}6$ cm. On complete blood count(CBC), leukocytosis and mild anemia were observed. Pulmonary metastasis was found in the thoracic radiographic examination. Blackish necrotic oral mass at the left mandibular area was diagnosed as a malignant melanoma based on the histopathological examination. Thus hemimadibulectomy and chemotherapy (carboplatin) were performed. The patient eventually died due to severe secondary infection 3 months after the last treatment.

구강내에 출혈을 동반한 크기 $5{\times}6$ 센티미터의 종괴가 있는 종양을 가진 12년령의 거세되지 않은 수컷 래브라도 리트리버가 건국대학교 부속동물병원에 의뢰되었다. 임상증상은 2년전부터 시작되었고, 점진적인 진행양상을 보여왔다. 총백혈구검사에서 백혈구증가증과 경도의 빈혈증상이 관찰되었다. 구강 종양의 폐장으로의 전이는 흉부 방사선 검사에서 발견되었으며 왼쪽 하악 주위의 흑색 괴저성의 종괴는 흡인도말검사 및 조직병리학적 검사에 의해 악성 흑색종으로 진단되었다. 치료는 외과적으로는 반하악절제술과 항암제인 carboplatin을 이용한 화학요법이 시행되었다. Carboplatin투여후 심한 신장의 괴사는 관찰되지 않았지만 이차감염으로 투여 3개월 후 폐사하였다.

Keywords

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