References
- Exp. Gerontol. v.31 Models of initiation of replicative senescence by loss of telomeric DNA Allsopp,R.C. https://doi.org/10.1016/0531-5565(95)02008-X
- Exp. Cell. Res. v.219 Evidence for a critical telomere lengh in senescent human fibroblast Allsopp,R.C.;Harley,C.B. https://doi.org/10.1006/excr.1995.1213
- Bioorg. Med. Chem. Lett. v.13 Inhibition of telomerase by BIBR 1532 and related analogues Barma,D.K.;Elayadi,A.;Falck,J.R.;Corey,D.R. https://doi.org/10.1016/S0960-894X(03)00101-X
- J. Cell. Sci. Suppl. v.10 Differentiation of fibroblast stem cells Bayreuther,K.;Rodemann,H.P.;Francz,P.I.;Maier,K.
- In vitro cell, Dev. Biol. v.14 The effect of donor age on the in vitro lifespan of cultured human arterial smooth-muscle cells Bierman,E.L. https://doi.org/10.1007/BF02616126
- Nature v.350 Structure and function of telomeres Blackburn,E. https://doi.org/10.1038/350569a0
- Science v.277 Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts Brown,J.P.;Wei,W.;Sedivy,J.M. https://doi.org/10.1126/science.277.5327.831
- Adv. Exp. Med. Biol. v.78 Mitochondrial production of superoxide radical and hydrogen peroxide Boveris,A. https://doi.org/10.1007/978-1-4615-9035-4_5
- Science v.279 Extension of life-span by introduction of telomerase into normal human cells Bondnar,A.G.;Ouellette,M.;Frolkis,M.;Holt,S.E.;Chiu,C.P.;Morin,G.B.;Harley,C.B.;Shay,J.W.;Lichtsteiner,S.;Wright,W.E. https://doi.org/10.1126/science.279.5349.349
- Cancer Res. v.55 Mutant p53 rescues human diploid cells from senescence without inhibithg in induction of SDI1/WAF1 Bond,J.A.;Blaydes,J.P.;Rowson,J.;Haugh,M.F.;Smith,J.R.;Wynford,T.D.;Wylie,F.S.
- Cell v.84 Replicative senescence: an old lives' tale? Campisi,J. https://doi.org/10.1016/S0092-8674(00)81023-5
- Lancet v.346 Cancer progression and p53 Carson,D.A.;Lois,A. https://doi.org/10.1016/S0140-6736(95)91693-8
- Prostate v.55 Cellular senescence in the pathogenesis of benign prostatic hyperplasia Castro,P.;Giri,D.;Lamb,D.;Ittmann,M. https://doi.org/10.1002/pros.10204
- Oncogene v.11 Telomerase activity in normal and malignant murine tissues Chadeneau,C.;Siegel,P.;Harley,C.B.;Muller,W.J.;Bacchetti,S.
- Proc. Natl. Acad. Sci. v.92 Oxidative DNA damage and senescence of human diploid fibroblast cells Chen,Q.;Fischer,A.;Reagan,J.D.;Yan,L.J.;Ames,B.N. https://doi.org/10.1073/pnas.92.10.4337
- Yan Ke Xue Bao. v.19 Inhibition on telomerase activity and cytotoxic effects by cisplatin in cultured human choroidal melanoma cells Cheng,H.;Wu,Z.;Zheng,J.;Lu,G.;Yan,J.;Liu,M.;Huang,D.;Lin,J.
- Proc. Soc. Exp. Biol. Med. v.214 Replicative senescence and cell immortality: the role of telomeres and telomerase Chiu,C.P.;Harley,C.B. https://doi.org/10.3181/00379727-214-44075
- Free Radic. Biol. Med. v.32 Iron release, oxidative stress and erythrocyte ageing Comporti,M.;Signorini,C.;Buonocore,G.;Ciccoli,L. https://doi.org/10.1016/S0891-5849(02)00759-1
- EMBO J. v.11 Telomere shorterning assocciated with chromosome instability is arrested in immortal cells which express telomerase activity Counter,C.M.;Avilion,A.A.;LeFeuvre,C.E.;Stewart,N.G.;Greider,C.W.;Narley,C.B.;Bacchetti,S.
- Virchows Arch. v.437 Telomeres, telomerase and cancer: an up-date Dhaene,K.;Van Marck,E.;Parwaresch,R. https://doi.org/10.1007/s004280000189
- Proc. Natl. Acad. Sci. v.92 A biomarker that identifies senescent human cells in culture and in aging skin in vivo Dimri,G.P.;Lee,X.;Basile,G.;Acosta,M.;Scott,G.;Roskelley,C.;Medrano,E.E.;Linskens,M.;Rubelj,I.;Pereira-Smith,O.;Peacocke,M.;Campisi,J. https://doi.org/10.1073/pnas.92.20.9363
- Gene Ther. v.8 Cell cycle arrest is sufficient for p53-mediated tumor regression Dubrez,L.;Coll,J.L.;Hurbin,A.;de Fraipont,F.;Lantejoul,S.;Favrot,M.C. https://doi.org/10.1038/sj.gt.3301592
- FEBS Lett. v.502 Growth kinetics rather than stress accelerate telomere shortening in cultures of human diploid fibroblasts in oxidative stress-induced premature senescence Dumont,P.;Royer,V.;Pascal,T.;Dierick,J.F.;Chainiaux,F.;Frippiat,C.;de Magalhaes,J.P.;Eliaers,F.;Remacle,J.;Toussaint,O. https://doi.org/10.1016/S0014-5793(01)02679-5
- Nat Genet. v.26 Telomere maintenance by recombination in human cells Dunham,M.A.;Neumann,A.A.;Fasching,C.L.;Reddel,R.R. https://doi.org/10.1038/82586
- Science v.269 The RNA component of human telomerase Feng,J.;Funk,W.D.;Wang,S.S.;Weinrich,S.L.;Avilion,A.A.;Chiu,C.P.;Adams,R.R.;Chang,E.;Allsopp,R.C.;Yu,J. https://doi.org/10.1126/science.7544491
- Cancer Res. v.60 Telomere erosion varies during in vitro aging of normal human fibroblasts from young and adult donors Figueroa,R.;Lindenmaier,H.;Hergenhahn,M.;Nielsen,K.V.;Boukamp,P.
- Life Sci. v.63 Age-dependent telomere shortening is slowed down by enrichment of intracellular vitamin C via suppression of oxidative stress Furumoto,K.;Inoue,E.;Nagao,N.;Hiyama,E.;Miwa,N. https://doi.org/10.1016/S0024-3205(98)00351-8
- Mol. Cell. Biol. v.15 Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint Garvik,B.;Carson,M.;Hartwell,L. https://doi.org/10.1128/MCB.15.11.6128
- Free Radic Res. v.35 Thyroid hormone-induced oxidative damage on lipids, glutathione and DNA in the mouse heart Gredilla,R.;Barja,G.;Lopez-Torres,M. https://doi.org/10.1080/10715760100300931
- Science v.249 Replicative senescence: the human fibroblast comes of age Goldstein,S.E. https://doi.org/10.1126/science.2204114
- Exp. Cell. Res. v.215 Genetic analysis of indefinite division in human cells: evidence for a common immotalizing mechanism in T and B lymphoid cell lines Goletz,T.J.;Robetorye,S.;Pereeira-Smith,O.M. https://doi.org/10.1006/excr.1994.1318
- Mol. Cell. Biol. v.16 Rat embryo fibroblasts immortalized with simian virus 40 large T antigen undergo senescence upon its inactivation Gonos,E.S.;Burns,J.S.;Mazars,G.R.;Koborna,A.;Riley,T.E.;Barnett,S.C.;Zafarana,G.;Ludwig,R.L.;Ikram,Z.;Powell,A.J.;Jat,P.S. https://doi.org/10.1128/MCB.16.9.5127
- Nippon Rinsho v.58 Werner syndrome Goto,M.;Ishikawa,Y.
- Mol. Pharmacol. v.60 Potent inhibition of telomerase by small-molecule pentacyclic acridines capable of interacting with G-quadruplexes Gowan,S.M.;Heald,R.;Stevens,M.F.;Kelland,L.R. https://doi.org/10.1124/mol.60.5.981
- Nat. Genet. v.17 The Werner syndrome protein is a DNA helicase Gray,M.D.;Shen,J.C.;Kamath-Loeb,A.S.;Blank,A.;Sopher,B.L.;Martin,G.M.;Oshima,J.;Loeb,L.A. https://doi.org/10.1038/ng0997-100
- FASEB J. v.15 Caloric restriction decreases mitochondrial free radical generation at complex I and lowers oxidative damage to mitochondrial DNA in the rat heart Gredilla,R.;Sanz,A.;Lopez-Torres,M.;Barja,G. https://doi.org/10.1096/fj.00-0764fje
- Microsc. Res. Tech. v.59 Effect of time of restriction on the decrease in mitochondrial H₂O₂production and oxidative DNA damage in the heart of food-restricted rats Gredilla,R.;Lopez-Torres,M.;Barja,G. https://doi.org/10.1002/jemt.10204
- Oncogene. v.18 Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation Greenberg,R.A.;O'Hagan,R.C.;Deng,H.;Xiao,Q.;Hann,S.R.;Adams,R.R.;Lichtsteiner,S.;Chin,L.;Morin,G.B.;DePinho,R.A. https://doi.org/10.1038/sj.onc.1202669
- Cell. v.97 Mammalian telomeres end in a large duplex loop Griffith,J.D.;Comeau,L.;Rosenfield,S.;Stansel,R.M.;Bianchi,A.;Moss,H.;de Lange,T. https://doi.org/10.1016/S0092-8674(00)80760-6
- Nature v.345 Telomeres shorten during ageing of human fibroblast Harley,C.B.;Futcher,A.B.;Greider,C.W. https://doi.org/10.1038/345458a0
- Cell v.75 The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases Harper,J.W.;Adami,G.R.;Wei,N.;Keyomarsi,K.;Elledge,S.J.
- Nature v.346 Telomere reduction in human colorectal carnoma and with ageing Hastie,N.D.;Dempster,M.;Dunlop,M.G.;Thompson,A.M.;Green,D.K.;Allshire,R.C. https://doi.org/10.1038/346866a0
- Exp. Cell. Res. v.37 The limited in vitro lifetime of human diploid cell strains Hayflick,L. https://doi.org/10.1016/0014-4827(65)90211-9
- N. Engl. Med. v.295 The cell biology of human aging Hayflick,L. https://doi.org/10.1056/NEJM197612022952308
- Am. J. Pathol. v.162 Telomere shortening and cellular senescence in a model of chronic renal allograft rejection Joosten,S.A.;Van Ham,V.;Nolan,C.E.;Borrias,M.C.;Jardine,A.G.;Shiels,P.G.;van Kooten,C.;Paul,L.C. https://doi.org/10.1016/S0002-9440(10)63926-0
- Science v.283 p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2 Karlseder,J.;Broccoli,D.;Dai,Y.;Hardy,S.;de Lange,T. https://doi.org/10.1126/science.283.5406.1321
- Mol. Pharmacol. v.63 Potent inhibition of human telomerase by nitrostyrene derivatives Kim,J.H.;Kim,J.H.;Lee,G.E.;Lee,J.E.;Chung,I.K. https://doi.org/10.1124/mol.63.5.1117
- J. Am. Chem. Soc. v.124 Telomestatin,a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex Kim,M.Y.;Vankayalapati,H.;Shin-Ya,K.;Wierzba,K.;Hurley,L.H. https://doi.org/10.1021/ja017308q
- Science v.266 Specific association of human telomerase activity with immortal cells and cancer Kim,N.W.;Piatyszek,M.A.;Prowse,K.R.;Harley,C.B.;West,M.D.;Ho,P.L.;Coviello,G.M.;Wright,W.E.;Weinrich,S.L.;Shay,J.W. https://doi.org/10.1126/science.7605428
- Nat. Genet. v.23 TIN2, a new regulator of telomere length in human cells Kim,S.H.;Kaminker,P.;Campisi,J. https://doi.org/10.1038/70508
- Exp. Cell Res. v.195 Fibronetin expression increases during in vitro cellular senescence; correlation with increased cell area Kumazaki,T.Robetorye,R.S.;Robetorye,S.C.;Smith,J.R. https://doi.org/10.1016/0014-4827(91)90494-F
- Science v.288 Extension of cell life-span and telomere length in animals cloned from senescent somatic cells Lanza,R.P.;Cibelli,J.B.;Blackwell,C.;Cristofalo,V.J.;Francis,M.K.;Baerlocher,G.M.;Mak,J.;Schertzer,M.;Chavez,E.A.;Sawyer,N.;Lansdorp,P.M.;West,M.D. https://doi.org/10.1126/science.288.5466.665
- Aging Cell. v.1 Mitochondrial dysfunction leads to telomere attrition and genomic instability Liu,L.;Trimarchi,J.R.;Smith,P.J.;Keefe,D.L. https://doi.org/10.1046/j.1474-9728.2002.00004.x
- Science v.232 Existemce of high abundance antiproliferative mRNAs in senescent human dipoid fibroblasts Lumpkin,C.K.;McClung,J.J.K. https://doi.org/10.1126/science.2421407
- Curr. Opin. Cell Biol. v.12 Genes involved in senescence and immortalization Lundberg,A.S.;Hahn,W.C.;Gupta,P.;Weinberg,R.A. https://doi.org/10.1016/S0955-0674(00)00155-1
- Cell. v.88 Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening Makarov,V.L.;Hirose,Y.;Langmore,J.P. https://doi.org/10.1016/S0092-8674(00)81908-X
- Exp. Gerontol. v.35 Caloric restriction and aging: an update Masoro,E.J. https://doi.org/10.1016/S0531-5565(00)00084-X
- Biorheology v.39 Human chondrocyte senescence and osteoarthritis Martin,J.A.;Buckwalter,J.A.
- J. Biol. Chem. v.277 Regulation of collagenase expression during replicative senescence in human fibroblasts by Akt-forkhead signaling Mawal-Dewan,M.;Lorenzini,A.;Frisoni,L.;Zhang,H.;Cristofalo,V.J.;Sell,C. https://doi.org/10.1074/jbc.M104515200
- Exp. Cell Res. v.285 Extension of replicative lifespan in WI-38 human fibroblasts by dexamethasone treatment is accompanied by suppression of p21 Waf1/Cip1/Sdi1 levels Mawal-Dewan,M.;Frisoni,L.;Cristofalo,V.J.;Sell,C. https://doi.org/10.1016/S0014-4827(03)00013-2
- Bratisl. Lek. Listy. v.103 Telomerase inhibitors in anticancer therapy: gossypol as a potential telomerase inhibitor Mego,M.
- Cell v.90 hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization Meyerson,M.;Counter,C.M.;Eaton,E.N.;Ellisen,L.W.;Steiner,P.;Caddle,S.D.;Ziaugra,L.;Beijersbergen,R.L.;Davidoff,M.J.;Liu,Q.;Bacchetti,S.;Haber,D.A.;Weinberg,R.A. https://doi.org/10.1016/S0092-8674(00)80538-3
- Exp. Cell Res. v.201 Differential expression of metalloproteinase and tissue inhibitor of metalloproteinase genes in aged human fibroblasts Millis,A.J.;Hoyle,M.;McCue,H.M.;Martini,H. https://doi.org/10.1016/0014-4827(92)90286-H
- Cancer Res. v.63 Simultaneous targeting of telomeres and telomerase as a cancer therapeutic approach Mo,Y.;Gan,Y.;Song,S.;Johnston,J.;Xiao,X.;Wientjies,M.G.;Au,J.L.
- Nucleic Acids Res. v.29 The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases Mohaghegh,P.;Karow,J.K.;Brosh,Jr,R.M.Jr; Bohr,V.A.;Hickson,I.D. https://doi.org/10.1093/nar/29.13.2843
- Mol. Cell. Biol. v.11 Diverse gene sequences are overexpressed in Waner syndrome fibroblasts undergoing premature replicative senescence Murano,S.;R.Thweatt;R.J.Shmookler-Reis;R.A.Jones;Moreman,E.J.;Goldstein,S. https://doi.org/10.1128/MCB.11.8.3905
- Nature v.299 Induction of immortality is an early event in malignant transformation of mammalian cells by carcinogenesis Newbold,R.F.;Overell,R.W.;Connell,J.R. https://doi.org/10.1038/299633a0
- Cell. v.88 TLP1: a gene encoding a protein component of mammalian telomerase is a novelmember of WD repeats family Nakayama,J.;Saito,M.;Nakamura,H.;Matsuura,A.;Ishikawa,F. https://doi.org/10.1016/S0092-8674(00)81933-9
- Genomics v.23 Intergrated mapping analysis of the werner syndrome region of chromosome 8 Oshima,J.;Chang,E.U.;Boennke,M.;Weber,J.L.;Edelhoff,S.;Wagner,M.J.;Wells,D.E.;Wood,S.;Disteche,C.M.;Martin,G.M.;Schllenberg,G.D. https://doi.org/10.1006/geno.1994.1464
- J. of Cell. Physi. v.162 Regulation of c-fos expression in senescencing werner syndrome fibroblasts differs from that observed in senescing fibroblasts from normal donors Oshima,J.;Campisi,J.;Tannock,T.C.A.;Martin,G.M. https://doi.org/10.1002/jcp.1041620213
- Mech. Ageing Dev. v.123 Oxidative, glycoxidative and lipoxidative damage to rat heart mitochondrial proteins is lower after 4 months of caloric restriction than in age-matched controls Pamplona,R.;Portero-Otin,M.;Requena,J.;Gredilla,R.;Barja,G. https://doi.org/10.1016/S0047-6374(02)00076-3
- Proc. Natl. Acad. Sci. v.85 Genetic analysis of indefinite division in human cells: identification of four complementation groups Pereira-Smith,O.M.;Smith,J.R. https://doi.org/10.1073/pnas.85.16.6042
- Exp. Cell. Res. v.239 Preferential accumulation of single-stranded regions in telomeres of human fibroblasts Petersen,S.;Saretzki,G.;von Zglinicki,T. https://doi.org/10.1006/excr.1997.3893
- Mech. Ageing Dev. v.123 Modelling telomere shortening and the role of oxidative stress Proctor,C.J.;Kirkwood,T.B. https://doi.org/10.1016/S0047-6374(01)00380-3
- Exp. Cell Res. v.227 Aging affects epidermal growth factor receptor phosphorylation and traffic kinetics Reenstra,W.R.;Yaar,M.;Gilchrest,B.A. https://doi.org/10.1006/excr.1996.0274
- Cancer Res. v.56 Elevated p16 at senescence and loss of p16 at immortalization in human papillomavirus E6, but not E7, transformed human uroepithelial cells Reznikoff,C.A.;Yeager,T.R.;Belair,C.D.;Savelieva,E.;Puthenveeyttil,J.A.;Stadler,W.M.
- Proc. Natl. Acad. Sci. v.89 Transcription factor AP-1 activity is required for initiaion of DNA synthesis and is lost during cellular aging Riabowol,K.;Schiff,J.;Gilman,M.Z. https://doi.org/10.1073/pnas.89.1.157
- Proc. Natl. Acad. Sci. v.78 Evidence for a relationship between longevity of mammalian species and life-spans of normal fibroblasts in vitro and erythrocytes in vivo Rohme,D. https://doi.org/10.1073/pnas.78.8.5009
- Env. Heal. Pers. v.93 Senescence as a mode of tumor suppression Sager,R. https://doi.org/10.1289/ehp.919359
- Lancet. v.358 Telomere shortening in atherosclerosis Samani,N.J.;Boultby,R.;Butler,R.;Thompson,J.R.;Goodall,A.H. https://doi.org/10.1016/S0140-6736(01)05633-1
- Ann. N. Y. Acad. Sci. v.959 Replicative aging, telomeres, and oxidative stress Saretzki,G.;Von Zglinicki,T. https://doi.org/10.1111/j.1749-6632.2002.tb02079.x
- Oncogene v.18 Telomere shortening triggers a p53-dependent cell cycle arrest via accumulation of G-rich single stranded DNA fragments Saretzki,G.;Sitte,N.;Merkel,U.;Wurm,R.E.;von Zglinicki,T. https://doi.org/10.1038/sj.onc.1202898
- Eur. J. Cancer v.33 A survey of telomerase activity in human cancer Shay,J.W.;Bacchetti,S. https://doi.org/10.1016/S0959-8049(97)00062-2
- Cell. v.102 Cellular senescence: mitotic clock or culture shock? Sherr,C.J.;DePinho,R.A. https://doi.org/10.1016/S0092-8674(00)00046-5
- Free Radic. Biol. Med. v.24 Accelerated telomere shortening in fibroblasts after extended periods of confluency Sitte,N.;Saretzki,G.;von Zglinicki,T. https://doi.org/10.1016/S0891-5849(97)00363-8
- J. Vasc. Surg. v.33 Senescence and the healing rates of venous ulcers Stanley,A.;Osler,T. https://doi.org/10.1067/mva.2001.115379
- Clin. Geriatr. Med. v.5 In vitro studies of aging Stanulis-Praeger,B.M.
- Science v.249 Failure to phosphorylate the retinoblastoma gene product in senescent human fibroblasts Stein,G.H.;Beeson,M.;Gordon,L. https://doi.org/10.1126/science.2166342
- Cancer Biol. Ther. v.2 Role of the retinoblastoma protein in differentiation and senescence Thomas,D.M.;Yang,H.S.;Alexander,K.;Hinds,P.W. https://doi.org/10.4161/cbt.2.2.235
- Exp. Gerontol. v.27 Isolation and characterization of gene sequences overexpressed in Werner syndrome fibroblasts during premature replicative senescence Thweatt,R.;Murano,S.;Fleischmann,R.D.;Goldstein,S. https://doi.org/10.1016/0531-5565(92)90078-E
- Pathol. Biol. v.42 Arguments in favour of the concept of critical threshold of accumulation of errors in cell death. Qualities and limits of this concept in cell aging Toussaint,O.;Remacle,J.
- Curr. Biol. v.8 Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span Vaziri,H.;Benchimol,S. https://doi.org/10.1016/S0960-9822(98)70109-5
- Biochemistry v.62 Critical telomere shortening regulated by the ataxia-telangiectasia gene acts as a DNA damage signal leading to activation of p53 protein and limited life-span of human diploid fibroblasts Vaziri,H.
- Exp. Gerontol. v.31 From telomere loss to p53 induction and activation of a DNA-damage pathway at senescence: the telomere loss/DNA damage model of cell aging Vaziri,H.;Benchimol,S. https://doi.org/10.1016/0531-5565(95)02025-X
- Exp. Cell Res. v.220 Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: a model for senescence? von Zglinicki,T.;Saretzki,G.;Docke,W.;Lotze,C. https://doi.org/10.1006/excr.1995.1305
- Free Radic. Biol. Med. v.28 Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts von Zglinicki,T.;Pilger,R.;Sitte,N. https://doi.org/10.1016/S0891-5849(99)00207-5
- Cancer Res. v.55 Senescent human fibroblast resist programmed cell death, and failure to suppress bcl2 is involved Wang,E.
- J. Cell. Biochem. v.54 Control of fibroblast senescence and activation of programmed cell death Wang,E.;Lee,M.J.;Pandey,S. https://doi.org/10.1002/jcb.240540410
- Cancer Res. v.59 Expression of catalytically active telomerase does not prevent premature senescence caused by overexpression of oncogenic Ha-Ras in normal human fibroblasts Wei,S.;Wei,W.;Sedivy,J.M.
- FASEB J. v.16 Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis Wiemann,S.U.;Satyanarayana,A.;Tsahuridu,M.;Tillmann,H.L.;Zender,L.;Klempnauer,J.;Flemming,P.;Franco,S.;Blasco,M.A.;Manns,M.P.;Rudolph,K.L. https://doi.org/10.1096/fj.01-0977com
- Crit. Rev. Oral. Biol. Med. v.13 P21Waf1 control of epithelial cell cycle and cell fate Weinberg,W.C.;Denning,M.F. https://doi.org/10.1177/154411130201300603
- Exp. Cell Res. v.184 Replicative senescence of human skin fibroblasts correlates with a loss of regulation and overexpression of collagenase activity West,M.D.;Pereira-Smith,O.M.;Smith,J.R. https://doi.org/10.1016/0014-4827(89)90372-8
- Ophthalmol. Vis. Sci. v.41 Relationship of telomeres and p53 in aging bovine corneal endothelial cell cultures Whikehart,D.R.;Register,S.J.;Chang,Q.;Montgomery,B.
- Nature v.421 Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing Wong,K.K.;Maser,R.S.;Bachoo,R.M.;Menon,J.;Carrasco,D.R.;Gu,Y.;Alt,F.W.;DePinho,R.A. https://doi.org/10.1038/nature01385
- Nat Med. v.6 Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse telomere biology Wright,W.E.;Shay,J.W. https://doi.org/10.1038/78592
- Nat. Genet. v.21 Direct activation of TERT transcription by c-MYC Wu,K.J.;Grandori,C.;Amacker,M.;Simon-Vermot,N.;Polack,A.;Lingner,J.;Dalla-Favera,R. https://doi.org/10.1038/6010
- Exp. Cell Res. v.285 Mutant p53 can delay growth arrest and loss of CDK2 activity in senescing human fibroblasts without reducing p21 (WAF1) expression Wyllie,F.;Haughton,M.;Bartek,J.;Rowson,J.;Wynford-Thomas,D. https://doi.org/10.1016/S0014-4827(03)00050-8
- FEBS Lett. v.470 Homocysteine accelerates entothelial cell senescence Xu,D.;Neville,R.;Finkel,T. https://doi.org/10.1016/S0014-5793(00)01278-3
- J. Biol. Chem. v.274 Human endothelial cell life extension by telomerase expression Yang,J.;Chang,E.;Cherry,A.M.;Bangs,C.D.;Oei,Y.;Bodnar,A.;Bronstein,A.;Chiu,C.P.;Herron,G.S. https://doi.org/10.1074/jbc.274.37.26141
- Exp. Cell Res. v.221 Increased expression of p21 Sdi1 in adrenocortical cells when they are placed in culture Yang,L.;Didenko,V.V.;Noda,A.;Bilyeu,T.A.;Darlington,G.J.;Smith,J.R.;Hornsby,P.J. https://doi.org/10.1006/excr.1995.1359
- Science v.272 Positional cloning of the werner's syndrome gene Yu,C.E.;Oshima,J.;Fu,Y.H.;Wijsman,E.M.;Hisama,F.;Alisch,R.;Matthews,S.;Nakura,J.;Miki,T.;Ouais,S.;Martin,G.M.;Mulligan,J.;Schellenberg,G.D. https://doi.org/10.1126/science.272.5259.258
- Exp. Cell Res. v.222 Differential regulation of collagenase and stromelysin mRNA in late passage cultures of human fibroblasts Zeng,G.;Millis,A.J. https://doi.org/10.1006/excr.1996.0019
- Oncogene. v.12 Regulation of p21WFI/CIP1 expression by p53-independent pathways Zeng,Y.X.;El-Deiry,W.S.
- Proc. Natl. Acad. Sci. v.96 Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening Zhu,J.;Wang,H.;Bishop,J.M.;Blackburn,E.H. https://doi.org/10.1073/pnas.96.7.3723
- Sheng Wu Gong Cheng Xue Bao. v.18 The effect of antioxidants on the in vitro life-span of keratinocyte Zhou,Y.;Ouyang,A.L.;Hua,P.;Tan,W.S.