YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Phytochemical Constituents from Cacalia koraiensis Nakai

참나래박쥐나물의 식물화학적 성분

  • 이성옥 (성균관대학교 약학대학 천연물약품화학연구실) ;
  • 최상진 (성균관대학교 약학대학 천연물약품화학연구실) ;
  • 양민철 (성균관대학교 약학대학 천연물약품화학연구실) ;
  • 정애경 (성균관대학교 약학대학 천연물약품화학연구실) ;
  • 남정환 (성균관대학교 약학대학 천연물약품화학연구실) ;
  • 이규하 (성균관대학교 약학대학 천연물약품화학연구실) ;
  • 이종순 (영남대학교 이과대학 생화학과) ;
  • 이강노 (성균관대학교 약학대학 천연물약품화학연구실)
  • Published : 2003.02.01
Download PDF
⟨ Previous Next ⟩

Abstract

The phytochemical study of Cacalia koraiensis Nakai (Compositae) led to the isolation of eight compounds, $\beta$-sitosterol (1), stigmasterol (2), phytol (3), $\beta$-sitosterol-3-Ο-glucopyranoside (4), adenostylol (5), campesterol (6), germacradien-4$\alpha$-ol (7), and quercetin-3-rhamnoside (8). Their structures were established by chemical and spectroscopic methods. The cytotoxicity of the isolated compounds was evaluated by SRB assay against five cultured human tumor cell lines.

Keywords

References

  1. 대한식물도감 이창복
  2. Planta Med. v.68 Eremophilane sesquiterpenes from Cacalia ainsliaeflora Mao, M.;Jia, Z. https://doi.org/10.1055/s-2002-19872
  3. J. Natl. Cancer Inst. v.82 New colorimetric cytotoxicity assay for anticancer-drug screening Skehan, P.;Storeng, R.;Scudiero, D.;Monks, A.;McMahon, J.;Vistica, D.;Warren, J. T.;Bokesch, H.;Kenney, S.;Boyd, M. R. https://doi.org/10.1093/jnci/82.13.1107
  4. Kor. J. Pharmacogn. v.32 Chemical components from the stem barks of Kalopanax septemlobus Hong, S. D.;Han, D. I.;Hwang, B. Y.;Choi, W. H.;Kang, H. S.;Lee. M. K.;Lee, M. K.;Lee, K. S.;Ro, J. S.
  5. Analysis of sterols Goad, L. J.
  6. Phytochemistry v.15 Isolation of free cis and trans-Phytop from the red Alga Gracilaria andersoniana Sims, J. J.;JR.;Pettus, J. A. https://doi.org/10.1016/S0031-9422(00)84413-1
  7. Natural Product Science v.6 Cardenolides and β-sitosterol glucoside grom Pergularia tomentosa L. Goher, A. A.;Olemy, M. M.;Sattar, E. A.;Said, M.;Niwa, M.
  8. Chem. Pharm. Bull. v.33 Furanoeremophilane-type sesquiterpenes from Cacalia adenostyoieds Kuroyanagi, M.;Naito, H.;Noro. T.;Ueno, A.;Fukushima, S. https://doi.org/10.1248/cpb.33.4792
  9. Phytochemistry v.16 Terpen-derivate aus senecio-arten Bohlmann, F.;Knoll, K. H.;Zdero, C.;Mahanta, P. K.;Grenz, M.;Suwita, A.;Ehlers. D.;Van, N. L.;Abraham, W. R.;Natu, A. A. https://doi.org/10.1016/S0031-9422(00)86705-9
  10. Phytochemistry v.51 Flavonoids from blue flowers of Nymphaea caerulea Fossen, T.;Larsen, A.;Kiremire, B. T.;Andersen, O. M. https://doi.org/10.1016/S0031-9422(99)00049-7