Biomolecules & Therapeutics

The Korean Society of Applied Pharmacology (한국응용약물학회)
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Tyrosinase Inhibitory Activity of 80 Plant Extracts (II)

  • Kim, Soo-Jin (College of Pharmacy, Kangwon National University) ;
  • Heo, Moon-Young (College of Pharmacy, Kangwon National University) ;
  • Son, Kun-Ho (Dept. Food Nutrition, Andong National University) ;
  • Kim, Hyun-Pyo (College of Pharmacy, Kangwon National University)
  • Published : 2003.03.01
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Abstract

The purpose of this study was to evaluate tyrosinase inhibitory activity of plant for extracts for cosmetic use. When 80 plant extracts were tested, the methanol extracts of Allium thunbergi, Asparagus oligoclonos, Ixeris dentate, Salvia plebeia, Sophora flavescens and Sophora japonica showed more than 30% inhibition of mushroom tyrosinase activity at 100 $\mu\textrm{g}$/mL. Although less active than the reference compound, kojic acid ($IC_{50}$=7.0-16.3 $\mu\textrm{g}$/mL), these plant extracts may be used as tyrosinase inhibitors in cosmetics.

Keywords

References

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